About: Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction     Goto   Sponge   NotDistinct   Permalink

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  • Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure.
  • Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure. (en)
Title
  • Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction
  • Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction (en)
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  • Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction
  • Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction (en)
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  • RIV/00216305:26620/13:PU104845!RIV15-MSM-26620___
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  • P(ED1.1.00/02.0068)
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  • 62665
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  • RIV/00216305:26620/13:PU104845
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  • metallothionein, Brdicka reaction, thiol compound, mercury electrode, tumour diseases, automation (en)
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  • [70D4F1314735]
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  • Voltammetry: Theory, Types and Applications
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  • Adam, Vojtěch
  • Hubálek, Jaromír
  • Hynek, David
  • Kizek, René
  • Trnková, Libuše
  • Tmejová, Kateřina
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  • Nova Science Publisher, Inc.
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  • 978-1-62948-057-2
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  • 26620
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