About: Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA (en)
Title	Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics (en)
skos:prefLabel	Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics (en)
skos:notation	RIV/00216305:26620/13:PU104425!RIV14-MSM-26620___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(EE2.3.30.0039), P(GAP301/10/0356)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Ryvolová, Markéta Chomoucká, Jana Adam, Vojtěch Hubálek, Jaromír Kizek, René
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	76712
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/13:PU104425
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Capillary electrophoresis, DNA, Gel electrophoresis, Platinum cytostatic drugs, Quantum dots (en)
http://linked.open.../riv/klicoveSlovo	Capillary electrophoresis Gel electrophoresis DNA Quantum dots Platinum cytostatic drugs
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[0A34D6637053]
http://linked.open...i/riv/nazevZdroje	Electrophoresis
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Excellent young researcher at BUT Central european institute of technology Study of contribution of different DNA-damaging mechanisms to toxicity of cytostatics to human chemosensitive and chemoresistant neuroblastomas
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	34
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Chomoucká, Jana Hubálek, Jaromír Kizek, René Vaculovičová, Markéta Šmerková, Kristýna
issn	0173-0835
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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