About: Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction     Goto   Sponge   NotDistinct   Permalink

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  • Metallothionein (MT) as a potential cancer marker is at the center of interest and its properties, function and behaviour under various condititons is intensively studied. In the present study, two major mammalian MT isoforms (MT-1 and MT-2) were separated using capillary electrophoresis (CE) coupled with UV detector in order to describe their basic behavior. The results were confirmed by manual spectrometric measurements and by different pulse voltammetry Brdicka reaction. Based on these results, a model of MT behaviour under the conditions studied was suggested.
  • Metallothionein (MT) as a potential cancer marker is at the center of interest and its properties, function and behaviour under various condititons is intensively studied. In the present study, two major mammalian MT isoforms (MT-1 and MT-2) were separated using capillary electrophoresis (CE) coupled with UV detector in order to describe their basic behavior. The results were confirmed by manual spectrometric measurements and by different pulse voltammetry Brdicka reaction. Based on these results, a model of MT behaviour under the conditions studied was suggested. (en)
Title
  • Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction
  • Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction (en)
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  • Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction
  • Structural changes in metallothionein isoforms revealed by capillary electrophoresis and Brdicka reaction (en)
skos:notation
  • RIV/00216305:26620/12:PU97473!RIV13-MSM-26620___
http://linked.open...avai/riv/aktivita
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  • P(ED1.1.00/02.0068), P(IAA401990701), P(KAN208130801), S
http://linked.open...iv/cisloPeriodika
  • 2
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  • 171808
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26620/12:PU97473
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  • Brdicka reaction, Cancer, CE, Denaturation, Electrochemistry, Isoforms, Metallothionein (en)
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  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [F06DE2F242FA]
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  • Electrophoresis
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  • 33
http://linked.open...iv/tvurceVysledku
  • Adam, Vojtěch
  • Hynek, David
  • Kizek, René
  • Provazník, Ivo
  • Vaculovičová, Markéta
  • Škutková, Helena
http://linked.open...ain/vavai/riv/wos
  • 000298849700002
issn
  • 0173-0835
number of pages
http://localhost/t...ganizacniJednotka
  • 26620
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