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  • Taurine (2-aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues. It is involved in many physiological processes. Thus, it is widely discussed especially due to its antioxidant properties. In this study, we focused on the effect of taurine supplementation on the concentration of antioxidants in blood plasma and erythrocytes of Wistar rats. Taurine was applied in feed mixture in the dosage of 0, 1, 250, 500, 750, 1000, 1500, 2000, 2500, 3000, 3500 and 4000 mg/kg. We monitored both enzymatic and non-enzymatic antioxidants - glutathione peroxidase, glutathione reductase, and superoxide dismutase and reduced/oxidized glutathione and metallothionein. Using three different methods 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), Ferric Reducing Antioxidant Power (FRAP) and free radicals, we determined antioxidant capacity. In addition, we monitored levels of uric acid and glucose. Our results revealed significant changes in both enzymatic and non-enzymatic parameters
  • Taurine (2-aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues. It is involved in many physiological processes. Thus, it is widely discussed especially due to its antioxidant properties. In this study, we focused on the effect of taurine supplementation on the concentration of antioxidants in blood plasma and erythrocytes of Wistar rats. Taurine was applied in feed mixture in the dosage of 0, 1, 250, 500, 750, 1000, 1500, 2000, 2500, 3000, 3500 and 4000 mg/kg. We monitored both enzymatic and non-enzymatic antioxidants - glutathione peroxidase, glutathione reductase, and superoxide dismutase and reduced/oxidized glutathione and metallothionein. Using three different methods 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), Ferric Reducing Antioxidant Power (FRAP) and free radicals, we determined antioxidant capacity. In addition, we monitored levels of uric acid and glucose. Our results revealed significant changes in both enzymatic and non-enzymatic parameters (en)
Title
  • Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach
  • Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach (en)
skos:prefLabel
  • Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach
  • Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach (en)
skos:notation
  • RIV/00216305:26220/14:PU112438!RIV15-MSM-26220___
http://linked.open...avai/riv/aktivita
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  • P(ED2.1.00/03.0072)
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  • 2
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  • 22698
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  • RIV/00216305:26220/14:PU112438
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  • Taurine, Thiol antioxidant, Oxidative stress, Glutathione, Metallothionein, Wistar rats (en)
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  • CZ - Česká republika
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  • [1C9D5D077103]
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  • J APPL BIOMED
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  • 12
http://linked.open...iv/tvurceVysledku
  • Adam, Vojtěch
  • Beklová, Miroslava
  • Babula, Petr
  • Cernei, Natalia Vladimirovna
  • Kizek, René
  • Pohanka, Miroslav
  • Sochor, Jiří
  • Zeman, Ladislav
  • Zítka, Ondřej
  • Mareš, Petr
  • Ruttkay-Nedecký, Branislav
  • Bezděková, Andrea
  • Lukešová, Kateřina
  • Nejdl, Lukáš
issn
  • 1214-021X
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.jab.2013.01.002
http://localhost/t...ganizacniJednotka
  • 26220
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