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  • Background and objective: Parkinsons disease (PD) is the second most common neurodegen-erative disease affecting significant portion of elderly population. One of the most frequenthallmarks and usually also the first manifestation of PD is deterioration of handwriting char-acterized by micrographia and changes in kinematics of handwriting. There is no objectivequantitative method of clinical diagnosis of PD. It is thought that PD can only be definitivelydiagnosed at postmortem, which further highlights the complexities of diagnosis.Methods: We exploit the fact that movement during handwriting of a text consists not onlyfrom the on-surface movements of the hand, but also from the in-air trajectories performedwhen the hand moves in the air from one stroke to the next. We used a digitizing tablet toassess both in-air and on-surface kinematic variables during handwriting of a sentence in37 PD patients on medication and 38 age- and gender-matched healthy controls.Results: By applying feature selection algo
  • Background and objective: Parkinsons disease (PD) is the second most common neurodegen-erative disease affecting significant portion of elderly population. One of the most frequenthallmarks and usually also the first manifestation of PD is deterioration of handwriting char-acterized by micrographia and changes in kinematics of handwriting. There is no objectivequantitative method of clinical diagnosis of PD. It is thought that PD can only be definitivelydiagnosed at postmortem, which further highlights the complexities of diagnosis.Methods: We exploit the fact that movement during handwriting of a text consists not onlyfrom the on-surface movements of the hand, but also from the in-air trajectories performedwhen the hand moves in the air from one stroke to the next. We used a digitizing tablet toassess both in-air and on-surface kinematic variables during handwriting of a sentence in37 PD patients on medication and 38 age- and gender-matched healthy controls.Results: By applying feature selection algo (en)
Title
  • Analysis of in-air movement in handwriting:A novel marker for Parkinsons disease
  • Analysis of in-air movement in handwriting:A novel marker for Parkinsons disease (en)
skos:prefLabel
  • Analysis of in-air movement in handwriting:A novel marker for Parkinsons disease
  • Analysis of in-air movement in handwriting:A novel marker for Parkinsons disease (en)
skos:notation
  • RIV/00216305:26220/14:PU111007!RIV15-MV0-26220___
http://linked.open...avai/riv/aktivita
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  • P(ED1.1.00/02.0068), P(ED2.1.00/03.0072), P(GAP102/12/1104), P(LD14091), P(NT13499), P(VG20102014033), S
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  • 3
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  • 2693
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  • RIV/00216305:26220/14:PU111007
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  • Handwriting, Disease classification, Parkinsons disease, Micrographia, In-air movement, Decision support systems (en)
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  • NL - Nizozemsko
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  • [D488433A8B31]
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  • COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
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  • 117
http://linked.open...iv/tvurceVysledku
  • Rektorová, Irena
  • Smékal, Zdeněk
  • Faúndez Zanuy, Marcos
  • Mekyska, Jiří
  • Drotár, Peter
  • Masarová, Lucia
issn
  • 0169-2607
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.cmpb.2014.08.007
http://localhost/t...ganizacniJednotka
  • 26220
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