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  • Dynamic contrast-enhanced ultrasound (DCE-US) imaging is a promising diagnostic method, which enables the evaluation of tissue perfusion via different parameters. The mean transit time and time-to-peak parameters are the main time parameters and their values depend on the model used for the approximation of the noisy perfusion curves. In this paper, we described a new comparison of different perfusion models using a tissue mimicking phantom. The following models were compared: log-normal, lagged, Erlang, Gamma and the local density random walk model. We discovered that the mean-square error is not the best criterion for model evaluation. More important is the comparison between the estimated time perfusion parameters and the physical parameters of the developed tissue mimicking phantom. Based on the statistical analysis, we can suggest that for the DCE-US perfusion analysis more models should be used, excluding the log-normal model, which gives the highest error of mean transit time value.
  • Dynamic contrast-enhanced ultrasound (DCE-US) imaging is a promising diagnostic method, which enables the evaluation of tissue perfusion via different parameters. The mean transit time and time-to-peak parameters are the main time parameters and their values depend on the model used for the approximation of the noisy perfusion curves. In this paper, we described a new comparison of different perfusion models using a tissue mimicking phantom. The following models were compared: log-normal, lagged, Erlang, Gamma and the local density random walk model. We discovered that the mean-square error is not the best criterion for model evaluation. More important is the comparison between the estimated time perfusion parameters and the physical parameters of the developed tissue mimicking phantom. Based on the statistical analysis, we can suggest that for the DCE-US perfusion analysis more models should be used, excluding the log-normal model, which gives the highest error of mean transit time value. (en)
Title
  • Comparison and evaluation of indicator dilution models for bolus of ultrasound contrast agents
  • Comparison and evaluation of indicator dilution models for bolus of ultrasound contrast agents (en)
skos:prefLabel
  • Comparison and evaluation of indicator dilution models for bolus of ultrasound contrast agents
  • Comparison and evaluation of indicator dilution models for bolus of ultrasound contrast agents (en)
skos:notation
  • RIV/00216305:26220/13:PU102196!RIV14-MSM-26220___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED1.100/02/0123), P(GAP102/12/2380), S
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 66124
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26220/13:PU102196
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ultrasonography, Contrast agent, Perfusion analysis, Perfusion models (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [7F742D4A7007]
http://linked.open...i/riv/nazevZdroje
  • PHYSIOLOGICAL MEASUREMENT
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 34
http://linked.open...iv/tvurceVysledku
  • Jiřík, Radovan
  • Kolář, Radim
  • Harabiš, Vratislav
  • Mézl, Martin
http://linked.open...ain/vavai/riv/wos
  • 000314287500004
issn
  • 0967-3334
number of pages
http://localhost/t...ganizacniJednotka
  • 26220
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