About: Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Voltage-sensitive dye (VSD) di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials (MAPs) in isolated hearts. In this study, its electrophysiological effects on rabbit and guinea pig myocardium were compared during staining with VSD and washout from it. Electrograms were recorded and heart rate changes and the types and frequency of arrhythmias were evaluated. Althought certain electrophysiological changes were present in the hearts of both species, these changes are mostly reversible, especially in rabbit hearts. Thus, rabbit myocardium can be considered a reliable model for electrophysiological studies, especially when generation and propagation of the impulse is studied. It may be concluded that rabbit isolated heart is more suitable model for electrophysiological studies in the isolated heart model than guinea pig heart. Voltage-sensitive dye (VSD) di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials (MAPs) in isolated hearts. In this study, its electrophysiological effects on rabbit and guinea pig myocardium were compared during staining with VSD and washout from it. Electrograms were recorded and heart rate changes and the types and frequency of arrhythmias were evaluated. Althought certain electrophysiological changes were present in the hearts of both species, these changes are mostly reversible, especially in rabbit hearts. Thus, rabbit myocardium can be considered a reliable model for electrophysiological studies, especially when generation and propagation of the impulse is studied. It may be concluded that rabbit isolated heart is more suitable model for electrophysiological studies in the isolated heart model than guinea pig heart. (en)
Title	Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart (en)
skos:prefLabel	Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart (en)
skos:notation	RIV/00216305:26220/10:PU87589!RIV11-GA0-26220___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA102/07/1473), Z(MSM0021630513)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Tannenberg, Milan Kolářová, Jana Fialová, Kateřina Provazník, Ivo Sekora, Jiří
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Fakulta elektrotechniky a komunikačních technologií
http://linked.open...dnocenehoVysledku	256800
http://linked.open...ai/riv/idVysledku	RIV/00216305:26220/10:PU87589
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Voltage-sensitive dye (VSD) di-4-ANEPPS, electrogram (en)
http://linked.open.../riv/klicoveSlovo	Voltage-sensitive dye (VSD) di-4-ANEPPS electrogram
http://linked.open...ontrolniKodProRIV	[C35F5C1CCFA4]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	Proceedings of Biosignal 2010: Analysis of Biomedical Signals and Images
http://linked.open...in/vavai/riv/obor	JD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Optical Methods for Registration of Heart Electrical Potentials and Calcium Concentration with Laser Stabilization
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Kolářová, Jana Provazník, Ivo Sekora, Jiří Fialová, Kateřina Nováková, Marie Tannenberg, Milan
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2010-06-27 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Advanced Electronic Communication Systems and Technologies (ELCOM)
number of pages	6 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Vysoké učení technické v Brně
https://schema.org/isbn	978-80-214-4106-4
http://localhost/t...ganizacniJednotka	26220

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