About: Model of Preconditioning in Guinea Pig and Rabbit Isolated Hearts Loaded with Voltage-Sensitive Dye Di-4-ANEPPS

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cardiovascular system diseases are frequent cause of morbidity and mortality in Western countries. In our laboratory, early stages of ischemia - prominent diagnosis in this group - are examined by recording electrograms and action potentials by optical probe in isolated mammalian hearts loaded with voltage-sensitive dye (VSD) di-4-ANEPPS. In this study, guinea pig and rabbit isolated hearts were exposed to special protocol of s.-c. preconditioning - attenuation of the symptoms during repeated exposure to ischemic insult. In guinea pig myocardium, additive effect of VSD and ischemia triggered more serious and more frequent arrhythmias then the same situation in rabbit hearts. Moreover, expected attenuation of these effects was not observed, on the contrary to rabbit myocardium, where typical preconditioning was present. Rabbit myocardium appears to be more suitable for studies in such experimental design. Cardiovascular system diseases are frequent cause of morbidity and mortality in Western countries. In our laboratory, early stages of ischemia - prominent diagnosis in this group - are examined by recording electrograms and action potentials by optical probe in isolated mammalian hearts loaded with voltage-sensitive dye (VSD) di-4-ANEPPS. In this study, guinea pig and rabbit isolated hearts were exposed to special protocol of s.-c. preconditioning - attenuation of the symptoms during repeated exposure to ischemic insult. In guinea pig myocardium, additive effect of VSD and ischemia triggered more serious and more frequent arrhythmias then the same situation in rabbit hearts. Moreover, expected attenuation of these effects was not observed, on the contrary to rabbit myocardium, where typical preconditioning was present. Rabbit myocardium appears to be more suitable for studies in such experimental design. (en)
Title	Model of Preconditioning in Guinea Pig and Rabbit Isolated Hearts Loaded with Voltage-Sensitive Dye Di-4-ANEPPS Model of Preconditioning in Guinea Pig and Rabbit Isolated Hearts Loaded with Voltage-Sensitive Dye Di-4-ANEPPS (en)
skos:prefLabel	Model of Preconditioning in Guinea Pig and Rabbit Isolated Hearts Loaded with Voltage-Sensitive Dye Di-4-ANEPPS Model of Preconditioning in Guinea Pig and Rabbit Isolated Hearts Loaded with Voltage-Sensitive Dye Di-4-ANEPPS (en)
skos:notation	RIV/00216305:26220/09:PU82547!RIV10-MSM-26220___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA102/07/1473), P(GP102/07/P521), Z(MSM0021630513)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kolářová, Jana Fialová, Kateřina Provazník, Ivo
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Fakulta elektrotechniky a komunikačních technologií
http://linked.open...dnocenehoVysledku	326688
http://linked.open...ai/riv/idVysledku	RIV/00216305:26220/09:PU82547
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Electrogram, monophasic action potential, animal experiment, cardiology research (en)
http://linked.open.../riv/klicoveSlovo	monophasic action potential animal experiment cardiology research Electrogram
http://linked.open...ontrolniKodProRIV	[91E7E166A6AB]
http://linked.open...v/mistoKonaniAkce	Park City, Utah
http://linked.open...i/riv/mistoVydani	Park City, Utah
http://linked.open...i/riv/nazevZdroje	Computers in Cardiology
http://linked.open...in/vavai/riv/obor	JD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Optical Methods for Registration of Heart Electrical Potentials and Calcium Concentration with Laser Stabilization Methods of analysis of mechanical and electrical activity of the heart in experimental cardiology
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Kolářová, Jana Provazník, Ivo Fialová, Kateřina Nováková, Marie
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2009-09-13 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Advanced Electronic Communication Systems and Technologies (ELCOM)
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	IEEE
https://schema.org/isbn	0-7803-8894-1
http://localhost/t...ganizacniJednotka	26220

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