| Attributes | Values |
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| rdf:type
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| Description
| - Parapapillary atrophy is an important clinical sign associated with progressive optic disc damage and visual field loss in patients with glaucoma. Histologic and spectroscopic results revealed an accumulation of lipofuscin as the dominant fundus fluorophore localized in the lysosomes of the retinal pigmentepithelium in the parapapillary atrophic zone. We investigated morphologic characteristics of parapapillary autofluorescence in patients with different entities and stages of glaucoma compared to healthy controls using Scanning Laser Ophthalmoscopy. Autofluorescence was measured with HRA standard software and compared to a new semiautomatic approach. Both, area and mean distance of the autofluorescence regions from the optic disc border were well associated with increasing glaucomatous damage. Changes were more pronounced for early stages. Semiautomatic segmentation improved interobserver variability.
- Parapapillary atrophy is an important clinical sign associated with progressive optic disc damage and visual field loss in patients with glaucoma. Histologic and spectroscopic results revealed an accumulation of lipofuscin as the dominant fundus fluorophore localized in the lysosomes of the retinal pigmentepithelium in the parapapillary atrophic zone. We investigated morphologic characteristics of parapapillary autofluorescence in patients with different entities and stages of glaucoma compared to healthy controls using Scanning Laser Ophthalmoscopy. Autofluorescence was measured with HRA standard software and compared to a new semiautomatic approach. Both, area and mean distance of the autofluorescence regions from the optic disc border were well associated with increasing glaucomatous damage. Changes were more pronounced for early stages. Semiautomatic segmentation improved interobserver variability. (en)
- Parapapillary atrophy is an important clinical sign associated with progressive optic disc damage and visual field loss in patients with glaucoma. Histologic and spectroscopic results revealed an accumulation of lipofuscin as the dominant fundus fluorophore localized in the lysosomes of the retinal pigmentepithelium in the parapapillary atrophic zone. We investigated morphologic characteristics of parapapillary autofluorescence in patients with different entities and stages of glaucoma compared to healthy controls using Scanning Laser Ophthalmoscopy. Autofluorescence was measured with HRA standard software and compared to a new semiautomatic approach. Both, area and mean distance of the autofluorescence regions from the optic disc border were well associated with increasing glaucomatous damage. Changes were more pronounced for early stages. Semiautomatic segmentation improved interobserver variability. (cs)
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| Title
| - Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects
- Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects (en)
- Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects (cs)
|
| skos:prefLabel
| - Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects
- Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects (en)
- Impact Of Parapapillary Autofluorescence In Glaucoma: Clinical Aspects (cs)
|
| skos:notation
| - RIV/00216305:26220/08:PU76141!RIV10-MSM-26220___
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(1M0572), Z(MSM0021630513)
|
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00216305:26220/08:PU76141
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - glaucoma, retinal imaging, autofluorescence (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Analysis of Biomedical Signals and Images
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Jan, Jiří
- Kolář, Radim
- Laemmer, Robert
- Mardin, Christian Y
|
| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
| |
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