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  • Ischemic preconditioning is a technique in which tissue is rendered resistant to the deleterious effects of prolonged ischemia and reperfusion by prior exposure to brief, repeated periods of vascular occlusion [Czech Cardiology Society, Medicine Word]. The hypothesis of ischemic preconditioning was first described at 1986 in [Murray], where it was demonstrated a 75 % reduction in infarct size caused by a 40 min coronary artery occlusion, when the occlusion was preceded by four episodes of 5 min ischemia and 5 min of reperfusion. Cardiac ischemia also causes beat-to-beat fluctuation in action potential duration which leads to T-wave alternans and arrhythmias [Qian]. Other studies describes links between action potenntial prolongation to cardiac alternans [Wilson]. This paper analyse action potentials recorded during repeated global ischemia and reperfusion in the experiment with rabbit hearts and verify the theory of ischemic preconditioning. In the experiment, optical mapping on the myocardium was use
  • Ischemic preconditioning is a technique in which tissue is rendered resistant to the deleterious effects of prolonged ischemia and reperfusion by prior exposure to brief, repeated periods of vascular occlusion [Czech Cardiology Society, Medicine Word]. The hypothesis of ischemic preconditioning was first described at 1986 in [Murray], where it was demonstrated a 75 % reduction in infarct size caused by a 40 min coronary artery occlusion, when the occlusion was preceded by four episodes of 5 min ischemia and 5 min of reperfusion. Cardiac ischemia also causes beat-to-beat fluctuation in action potential duration which leads to T-wave alternans and arrhythmias [Qian]. Other studies describes links between action potenntial prolongation to cardiac alternans [Wilson]. This paper analyse action potentials recorded during repeated global ischemia and reperfusion in the experiment with rabbit hearts and verify the theory of ischemic preconditioning. In the experiment, optical mapping on the myocardium was use (en)
Title
  • The Evolution of Action Potential during Repeated Ischemia in Rabbit Myocardium
  • The Evolution of Action Potential during Repeated Ischemia in Rabbit Myocardium (en)
skos:prefLabel
  • The Evolution of Action Potential during Repeated Ischemia in Rabbit Myocardium
  • The Evolution of Action Potential during Repeated Ischemia in Rabbit Myocardium (en)
skos:notation
  • RIV/00216305:26220/08:PU72991!RIV10-MSM-26220___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA102/07/1473), P(GP102/07/P521), Z(MSM0021630513)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 366926
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26220/08:PU72991
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Action Potentials, Repeated Ischemia, Rabbit Myocardium (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [E38C4109E5AC]
http://linked.open...i/riv/nazevZdroje
  • Analysis of Biomedical Signals and Images
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 19
http://linked.open...iv/tvurceVysledku
  • Kolářová, Jana
  • Provazník, Ivo
  • Sekora, Jiří
  • Švrček, Martin
http://linked.open...n/vavai/riv/zamer
issn
  • 1211-412X
number of pages
http://localhost/t...ganizacniJednotka
  • 26220
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