About: Comparison of methods for evaluation of aerosol deposition in the model of human lungs

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	It seems to be very convenient to receive a medicine by inhalation instead of injection. Unfortunately transport of particles and targeted delivery of a drug in human respiratory airways is very complicated task. Therefore we carried out experiments and tested different methods for evaluation of particle deposition in a model of human lungs. The model included respiratory airways from oral cavity to 7th generation of branching. Particles were dispersed by TSI Small-scale Powder Disperser 3433 and delivered to the model. The model was disassembled into segments after the deposition of the particles and local deposition was measured. Two methods were used to analyse the samples, fluorescence spectroscopy and optical microscopy. The first method was based on measuring the intensity of luminescence, which represented the particle deposition. The second method used the optical microscope with phase-contrast objective. A dispersion of isopropanol and particles was filtrated using a vacuum filtration unit, a It seems to be very convenient to receive a medicine by inhalation instead of injection. Unfortunately transport of particles and targeted delivery of a drug in human respiratory airways is very complicated task. Therefore we carried out experiments and tested different methods for evaluation of particle deposition in a model of human lungs. The model included respiratory airways from oral cavity to 7th generation of branching. Particles were dispersed by TSI Small-scale Powder Disperser 3433 and delivered to the model. The model was disassembled into segments after the deposition of the particles and local deposition was measured. Two methods were used to analyse the samples, fluorescence spectroscopy and optical microscopy. The first method was based on measuring the intensity of luminescence, which represented the particle deposition. The second method used the optical microscope with phase-contrast objective. A dispersion of isopropanol and particles was filtrated using a vacuum filtration unit, a (en)
Title	Comparison of methods for evaluation of aerosol deposition in the model of human lungs Comparison of methods for evaluation of aerosol deposition in the model of human lungs (en)
skos:prefLabel	Comparison of methods for evaluation of aerosol deposition in the model of human lungs Comparison of methods for evaluation of aerosol deposition in the model of human lungs (en)
skos:notation	RIV/00216305:26210/13:PU106786!RIV14-GA0-26210___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED0002/01/01), P(GAP105/11/1339)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Lippay, Josef Lízal, František Jícha, Miroslav Jedelský, Jan Bělka, Miloslav
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Fakulta strojního inženýrství
http://linked.open...dnocenehoVysledku	66251
http://linked.open...ai/riv/idVysledku	RIV/00216305:26210/13:PU106786
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Aerosol deposition, optical microscopy, fluorescent spectroscopy, human lungs (en)
http://linked.open.../riv/klicoveSlovo	human lungs fluorescent spectroscopy Aerosol deposition optical microscopy
http://linked.open...ontrolniKodProRIV	[03662EF1C79D]
http://linked.open...v/mistoKonaniAkce	Kutná Hora
http://linked.open...i/riv/mistoVydani	Kutná hora
http://linked.open...i/riv/nazevZdroje	International Conference Experimental Fluid Mechanics 2013
http://linked.open...in/vavai/riv/obor	BK
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	NETME Centre (New Technologies for Mechanical Engineering) Porous particle-laden turbulent and laminar oscillating and steady flow in multiple branching
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Jedelský, Jan Jícha, Miroslav Lippay, Josef Lízal, František Bělka, Miloslav
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2013-11-19 (xsd:date)
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Technical university of Liberec
https://schema.org/isbn	978-80-260-5375-0
http://localhost/t...ganizacniJednotka	26210

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