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  • In vitro studies of aerosol transport in human airway models give considerable information for advancement of targeted drug delivery and serve for validation of numerical simulations where more accurate turbulence models are needed. We applied a semi-realistic transparent model of human airways for a study of flow of micron-sized spherical particles dispersed in air using Phase Doppler Anemometry (PDA). The model is based on CT scans of human lungs and encompasses mouth cavity, realistic glottal geometry and three to four generations of bronchi with 3D branching. Cylindrical tubes were used to replace original rough and warped walls of airway channels. 1D PDA with classical optics was used for measurement of time-resolved velocity of particle-laden air flow in multiple points of the optically transparent model. Aerosol particles of DEHS with 3 um in diameter were produced by CMAG, mixed with air in a static mixer and resulting dilute dispersed two-phase mixture was led to the lung model. Mean axial ve
  • In vitro studies of aerosol transport in human airway models give considerable information for advancement of targeted drug delivery and serve for validation of numerical simulations where more accurate turbulence models are needed. We applied a semi-realistic transparent model of human airways for a study of flow of micron-sized spherical particles dispersed in air using Phase Doppler Anemometry (PDA). The model is based on CT scans of human lungs and encompasses mouth cavity, realistic glottal geometry and three to four generations of bronchi with 3D branching. Cylindrical tubes were used to replace original rough and warped walls of airway channels. 1D PDA with classical optics was used for measurement of time-resolved velocity of particle-laden air flow in multiple points of the optically transparent model. Aerosol particles of DEHS with 3 um in diameter were produced by CMAG, mixed with air in a static mixer and resulting dilute dispersed two-phase mixture was led to the lung model. Mean axial ve (en)
Title
  • Experimental study of aerosol transport in semi-realistic human airway model
  • Experimental study of aerosol transport in semi-realistic human airway model (en)
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  • Experimental study of aerosol transport in semi-realistic human airway model
  • Experimental study of aerosol transport in semi-realistic human airway model (en)
skos:notation
  • RIV/00216305:26210/12:PU99687!RIV13-MSM-26210___
http://linked.open...avai/riv/aktivita
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  • P(ME09030), P(OC10052)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 135627
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  • RIV/00216305:26210/12:PU99687
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • PARTICLE-LADEN AIR FLOW, SEMI-REALISTIC MODEL, HUMAN AIRWAYS (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [F437D1646EEF]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Jedelský, Jan
  • Jícha, Miroslav
  • Lízal, František
  • Elcner, Jakub
http://localhost/t...ganizacniJednotka
  • 26210
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