About: Tensegrity finite element models of mechanical tests of individual cells

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A three-dimensional finite element model of a vascular smooth muscle cell is based on models published recently; it comprehends elements representing cell membrane, cytoplasm and nucleus, and a complex tensegrity structure representing the cytoskeleton. In contrast to previous models of eucaryotic cells, this tensegrity structure consists of several parts. Its external and internal parts number 30 struts, 60 cables each, and their nodes are interconnected by 30 radial members; these parts represent cortical, nuclear and deep cytoskeletons, respectively. This arrangement enables us to simulate load transmission from the extracellular space to the nucleus or centrosome via membrane receptors (focal adhesions); the ability of the model was tested by simulation of some mechanical tests with isolated vascular smooth muscle cells. Although material properties of components defined on the basis of the mechanical tests are ambiguous, modelling of different types of tests has shown the ability of the model to A three-dimensional finite element model of a vascular smooth muscle cell is based on models published recently; it comprehends elements representing cell membrane, cytoplasm and nucleus, and a complex tensegrity structure representing the cytoskeleton. In contrast to previous models of eucaryotic cells, this tensegrity structure consists of several parts. Its external and internal parts number 30 struts, 60 cables each, and their nodes are interconnected by 30 radial members; these parts represent cortical, nuclear and deep cytoskeletons, respectively. This arrangement enables us to simulate load transmission from the extracellular space to the nucleus or centrosome via membrane receptors (focal adhesions); the ability of the model was tested by simulation of some mechanical tests with isolated vascular smooth muscle cells. Although material properties of components defined on the basis of the mechanical tests are ambiguous, modelling of different types of tests has shown the ability of the model to (en)
Title	Tensegrity finite element models of mechanical tests of individual cells Tensegrity finite element models of mechanical tests of individual cells (en)
skos:prefLabel	Tensegrity finite element models of mechanical tests of individual cells Tensegrity finite element models of mechanical tests of individual cells (en)
skos:notation	RIV/00216305:26210/12:PU96461!RIV13-GA0-26210___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA106/09/1732)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Lebiš, Radek Burša, Jiří Holata, Jakub
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Fakulta strojního inženýrství
http://linked.open...dnocenehoVysledku	173752
http://linked.open...ai/riv/idVysledku	RIV/00216305:26210/12:PU96461
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cell biomechanics, Tensegrity structure, Cytoskeleton, Computational model (en)
http://linked.open.../riv/klicoveSlovo	Cell biomechanics Computational model Cytoskeleton Tensegrity structure
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[0F2A59B48A6D]
http://linked.open...i/riv/nazevZdroje	Technology and Health Care, Int. Journal of Health Care Engineering
http://linked.open...in/vavai/riv/obor	JJ
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	MULTISCALE MODELLING OF BEHAVIOUR OF HYPERELASTIC ANISOTROPIC MATERIALS
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	20
http://linked.open...iv/tvurceVysledku	Burša, Jiří Holata, Jakub Lebiš, Radek
issn	0928-7329
number of pages	16 (xsd:int)
http://localhost/t...ganizacniJednotka	26210

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