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  • Transport of aerosol particles in respiratory tract attracts more and more attention in view of tar-geted delivery of therapeutic sprays to treat wide spectrum of not only pulmonary diseases. To enable optical measurement of aerosol transport with air as working fluid, we created realistic thin-walled transparent airway model. The non-symmetric bifurcation model reflects real non-planar lung geometry and spans from throat to 3rd-4th generation of bronchi. A pneumatic mecha-nism generated oscillating air flow into the model. Monodisperse droplets were mixed with air at the model entry. Velocity and size measurement of the particles were done using Phase/Doppler Particle Analyzer (P/DPA). Difference between air supply from the %22mouth side%22 and the %22alveoli side%22 into simple bifurcation lung model was investigated. We observed increased turbulence intensity especially during expira-tion phase in case of the mouth side control compared to alveoli side control. The reason of this distinction is different
  • Transport of aerosol particles in respiratory tract attracts more and more attention in view of tar-geted delivery of therapeutic sprays to treat wide spectrum of not only pulmonary diseases. To enable optical measurement of aerosol transport with air as working fluid, we created realistic thin-walled transparent airway model. The non-symmetric bifurcation model reflects real non-planar lung geometry and spans from throat to 3rd-4th generation of bronchi. A pneumatic mecha-nism generated oscillating air flow into the model. Monodisperse droplets were mixed with air at the model entry. Velocity and size measurement of the particles were done using Phase/Doppler Particle Analyzer (P/DPA). Difference between air supply from the %22mouth side%22 and the %22alveoli side%22 into simple bifurcation lung model was investigated. We observed increased turbulence intensity especially during expira-tion phase in case of the mouth side control compared to alveoli side control. The reason of this distinction is different (en)
Title
  • Study of Droplet Transport and Deposition in Human Airways under Realistic Conditions
  • Study of Droplet Transport and Deposition in Human Airways under Realistic Conditions (en)
skos:prefLabel
  • Study of Droplet Transport and Deposition in Human Airways under Realistic Conditions
  • Study of Droplet Transport and Deposition in Human Airways under Realistic Conditions (en)
skos:notation
  • RIV/00216305:26210/09:PU83591!RIV10-GA0-26210___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA101/07/0862)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 344453
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  • RIV/00216305:26210/09:PU83591
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  • therapeutic sprays, aerosol transport, cyclic respiration, particle deposition, human airways (en)
http://linked.open.../riv/klicoveSlovo
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  • [4528B9EF5F5C]
http://linked.open...in/vavai/riv/obor
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http://linked.open...iv/tvurceVysledku
  • Jedelský, Jan
  • Jícha, Miroslav
  • Lízal, František
  • Bergmann, Ralf
  • Košner, Jan
  • Hampel, Uwe
http://localhost/t...ganizacniJednotka
  • 26210
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