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  • In past decades, capillary electromigration separation methods have been established as the routine techniques suitable for the analyzes of ionized and non-ionized compounds. The improvement in sensitivity of detection lead to discoveries of new substances presented at trace levels in various samples. For determination of such compounds, separation methods with high resolving power are needed, which leads to the rapid development of 2D methods. The article reviews some experimental aspects and applications of CE in the 2D separation systems, focused mainly to its combinations with LC. CE is being applied in 2D systems either in both or presumably in the 2nd dimension due to the speed of the analysis and injected volumes of samples. Advantages and drawbacks of the off-line and on-line experimental setups are discussed. Applications of 2D LC-CE are discussed with special emphasis on the possibilities of improvement of the detection sensitivity using in-capillary preconcentration techniques.
  • In past decades, capillary electromigration separation methods have been established as the routine techniques suitable for the analyzes of ionized and non-ionized compounds. The improvement in sensitivity of detection lead to discoveries of new substances presented at trace levels in various samples. For determination of such compounds, separation methods with high resolving power are needed, which leads to the rapid development of 2D methods. The article reviews some experimental aspects and applications of CE in the 2D separation systems, focused mainly to its combinations with LC. CE is being applied in 2D systems either in both or presumably in the 2nd dimension due to the speed of the analysis and injected volumes of samples. Advantages and drawbacks of the off-line and on-line experimental setups are discussed. Applications of 2D LC-CE are discussed with special emphasis on the possibilities of improvement of the detection sensitivity using in-capillary preconcentration techniques. (en)
Title
  • Capillary Electrophoresis in Multidimensional Separation Techniques For Analysis of Natural Compounds in Complex Matrices (A Review)
  • Capillary Electrophoresis in Multidimensional Separation Techniques For Analysis of Natural Compounds in Complex Matrices (A Review) (en)
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  • Capillary Electrophoresis in Multidimensional Separation Techniques For Analysis of Natural Compounds in Complex Matrices (A Review)
  • Capillary Electrophoresis in Multidimensional Separation Techniques For Analysis of Natural Compounds in Complex Matrices (A Review) (en)
skos:notation
  • RIV/00216275:25310/11:39891995!RIV12-GA0-25310___
http://linked.open...avai/riv/aktivita
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  • P(GP203/09/P199), Z(MSM0021627502)
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  • 189135
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  • RIV/00216275:25310/11:39891995
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  • Review; Natural compounds; On-line preconcentration; Orthogonality; Two-dimensional separations; Micellar electrokinetic capillary chromatography; Capillary electrophoresis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [017A42DB0106]
http://linked.open...v/mistoKonaniAkce
  • Pardubice
http://linked.open...i/riv/mistoVydani
  • Pardubice
http://linked.open...i/riv/nazevZdroje
  • Sensing in Electroanalysis Vol. 6
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Dinisová, Petra
  • Fischer, Jan
  • Česla, Petr
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http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Univerzita Pardubice
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  • 978-80-7395-434-5
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  • 25310
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