About: Inverse Correlation between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The interrelationships between plasma beta-carotene, alpha-tocopherol, and the level of systemic inflammation and oxidative stress were investigated in patients with advanced coronary artery disease (CAD). Plasma b-carotene, a-tocopherol, malondialdehyde, free radicals, interleukin-6, high sensitive C-reactive protein, and other risk factors of CAD were determined in a group of patients with advanced CAD (significant stenosis according to coronarographic examination; n=91) and control group of examined patients with coronary arteries with no stenosis (n=49). Between-group differences in continuous variables were analyzed with the Hotelling T2-test (software NCSS2000), analyses of correlation matrix with the software STATISTICA. Advanced CAD coincided with significantly lower plasma concentrations of HDL-cholesterol and b-carotene as well as with elevated levels of all inflammatory markers, but only with mild increase of oxidative stress. B-Carotene significantly inversely correlated with interleukin-6. This inverse correlation could suggest potential protective effect of b-carotene on atherosclerosis due to the inhibition of inflammatory processes. The interrelationships between plasma beta-carotene, alpha-tocopherol, and the level of systemic inflammation and oxidative stress were investigated in patients with advanced coronary artery disease (CAD). Plasma b-carotene, a-tocopherol, malondialdehyde, free radicals, interleukin-6, high sensitive C-reactive protein, and other risk factors of CAD were determined in a group of patients with advanced CAD (significant stenosis according to coronarographic examination; n=91) and control group of examined patients with coronary arteries with no stenosis (n=49). Between-group differences in continuous variables were analyzed with the Hotelling T2-test (software NCSS2000), analyses of correlation matrix with the software STATISTICA. Advanced CAD coincided with significantly lower plasma concentrations of HDL-cholesterol and b-carotene as well as with elevated levels of all inflammatory markers, but only with mild increase of oxidative stress. B-Carotene significantly inversely correlated with interleukin-6. This inverse correlation could suggest potential protective effect of b-carotene on atherosclerosis due to the inhibition of inflammatory processes. (en)
Title	Inverse Correlation between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease Inverse Correlation between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease (en)
skos:prefLabel	Inverse Correlation between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease Inverse Correlation between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease (en)
skos:notation	RIV/00216275:25310/10:39881934!RIV12-MSM-25310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OC 124), Z(MSM0021627502)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kanďár, Roman Meloun, Milan Královec, Karel Mužáková, Vladimíra Žáková, Pavla
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Pardubice / Fakulta chemicko-technologická
http://linked.open...dnocenehoVysledku	264775
http://linked.open...ai/riv/idVysledku	RIV/00216275:25310/10:39881934
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Atherosclerosis; Interleukin-6; Beta-Carotene (en)
http://linked.open.../riv/klicoveSlovo	Atherosclerosis Beta-Carotene Interleukin-6
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[1F196D30A256]
http://linked.open...i/riv/nazevZdroje	International Journal for Vitamin and Nutrition Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20124
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	80
http://linked.open...iv/tvurceVysledku	Kanďár, Roman Skalický, Jiří Meloun, Milan Žáková, Pavla Vojtíšek, Petr Královec, Karel Mužáková, Vladimíra
http://linked.open...ain/vavai/riv/wos	000294506900002
http://linked.open...n/vavai/riv/zamer	Pokročilé analytické a separační metody a jejich aplikace v diagnostice a technologii živých a neživých materiálů
issn	0300-9831
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1024/0300-9831/a000024
http://localhost/t...ganizacniJednotka	25310

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