About: Oxidative stress and its impact on development of advanced coronary artery disease

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Background. The disbalance of redox equilibrium plays a role in development of atherosclerosis. The aim of this study was to asses the impact of oxidative stress and antioxidative status in patients with advanced coronary artery disease. Methods. Oxidative stress parameters were determined in group of patients with serious coronary artery disease (at least 50% stenosis of the left main coronary artery or 70% stenosis of other coronary artery according to coronarographic examination; S,n=40) and control group with normal coronary artery status (C,n=38). Free radical concentration was determined by spectrophotometric assay based on chlorophyllin acceptance of electrons, total antioxidant capacity using kit TAS (Randox, UK), malondialdehyde, glutathione and a-tocopherol plasma concentration by HPLC. Plasma levels of allantoin, a-1antiproteinase, total cholesterol, triglycerides, HDL-ch, LDL-ch, fibrinogen and hsCRP were followed. Results. In patients with coronary stenosis (S) higher level of free ra Background. The disbalance of redox equilibrium plays a role in development of atherosclerosis. The aim of this study was to asses the impact of oxidative stress and antioxidative status in patients with advanced coronary artery disease. Methods. Oxidative stress parameters were determined in group of patients with serious coronary artery disease (at least 50% stenosis of the left main coronary artery or 70% stenosis of other coronary artery according to coronarographic examination; S,n=40) and control group with normal coronary artery status (C,n=38). Free radical concentration was determined by spectrophotometric assay based on chlorophyllin acceptance of electrons, total antioxidant capacity using kit TAS (Randox, UK), malondialdehyde, glutathione and a-tocopherol plasma concentration by HPLC. Plasma levels of allantoin, a-1antiproteinase, total cholesterol, triglycerides, HDL-ch, LDL-ch, fibrinogen and hsCRP were followed. Results. In patients with coronary stenosis (S) higher level of free ra (en) Oxidační stres a jeho význam pro rozvoj onemocnění koronárních tepen (cs)
Title	Oxidative stress and its impact on development of advanced coronary artery disease Oxidative stress and its impact on development of advanced coronary artery disease (en) Oxidační stres a jeho význam pro rozvoj onemocnění koronárních tepen (cs)
skos:prefLabel	Oxidative stress and its impact on development of advanced coronary artery disease Oxidative stress and its impact on development of advanced coronary artery disease (en) Oxidační stres a jeho význam pro rozvoj onemocnění koronárních tepen (cs)
skos:notation	RIV/00216275:25310/07:00006584!RIV08-MSM-25310___
http://linked.open.../vavai/riv/strany	S241
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OC 124), Z(MSM0021627502)
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Roušar, Tomáš Kanďár, Roman Meloun, Milan Mužáková, Vladimíra
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Pardubice / Fakulta chemicko-technologická
http://linked.open...dnocenehoVysledku	440392
http://linked.open...ai/riv/idVysledku	RIV/00216275:25310/07:00006584
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	oxidative stress; coronary artery disease (en)
http://linked.open.../riv/klicoveSlovo	coronary artery disease oxidative stress
http://linked.open...ontrolniKodProRIV	[0FBEA5EC3DD5]
http://linked.open...i/riv/mistoVydani	Berlin
http://linked.open...i/riv/nazevZdroje	Clinical Chemistry and Laboratory Medicine
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20124
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Kanďár, Roman Roušar, Tomáš Skalický, Jiří Meloun, Milan Vojtíšek, Petr Mužáková, Vladimíra Kovařík, Jakub
http://linked.open...n/vavai/riv/zamer	Pokročilé analytické a separační metody a jejich aplikace v diagnostice a technologii živých a neživých materiálů
issn	1434-6621
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Walter de Gruyter GmbH & Co. KG
http://localhost/t...ganizacniJednotka	25310

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