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| Description
| - Background. We studied the relation between plasma total homocysteine and cysteine levels in men with positive and negative angiographic findings. The negative finding was defined as no stenosis in coronary arteries. The positive result was characterized as 70% or more stenosis in coronary arteries or as 50% or more stenosis in arteria coronaria sinistra. Methods. The degree of stenosis was determined by coronary angiography. Both of analytes were measured simultaneously using ion-paired HPLC method with coulometric detection. Results. We compared this method with HPLC method with fluorescence detection by linear regression: HPLC/ED = 1.1435 (HPLC/FD) ? 0.273 umol/l, R2 = 0.9945 for homocysteine and HPLC/ED = 0.8737 (HPLC/FD) + 56.534 umol/l, R2 = 0.8564 for cysteine. The significant positive correlation between levels of cysteine and homocysteine was found in the angiographically negative group (r = 0.506, p = 0.044). In contrast to this finding, there was no significantly correlation in patients
- Background. We studied the relation between plasma total homocysteine and cysteine levels in men with positive and negative angiographic findings. The negative finding was defined as no stenosis in coronary arteries. The positive result was characterized as 70% or more stenosis in coronary arteries or as 50% or more stenosis in arteria coronaria sinistra. Methods. The degree of stenosis was determined by coronary angiography. Both of analytes were measured simultaneously using ion-paired HPLC method with coulometric detection. Results. We compared this method with HPLC method with fluorescence detection by linear regression: HPLC/ED = 1.1435 (HPLC/FD) ? 0.273 umol/l, R2 = 0.9945 for homocysteine and HPLC/ED = 0.8737 (HPLC/FD) + 56.534 umol/l, R2 = 0.8564 for cysteine. The significant positive correlation between levels of cysteine and homocysteine was found in the angiographically negative group (r = 0.506, p = 0.044). In contrast to this finding, there was no significantly correlation in patients (en)
- Úvod. Studovali jsme vztah mezi hladinami homocysteinu a cysteinu v plazmě u pacientů s pozitivním a negativním angiografickým nálezem. Negativní nález byl definován jako žádná stenóza ve věnčitých cévách. Pozitivní nález byl charakterizován jako 70% a větší stenóza ve věnčitých cévách nebo jako 50% a větší stenóza v arteria coronaria sinistra. Metody. Stupeň stenózy byl určen pomocí koronární angiografie. Oba analyty byly měřeny simultánně pomocí ion párové chromatografie s coulometrickou detekcí. Výsledky. Pomocí lineární regrese jsme porovnali naši metodu s metodou HPLC s fluorescenční detekcí: HPLC/ED = 1,1435 (HPLC/FD) ? 0,273 umol/l, R2 = 0,9945 pro homocystein a HPLC/ED = 0,8737 (HPLC/FD) + 56,534 umol/l, R2 = 0,8564 pro cystein. U skupiny pacientů s negativním angiografickým nálezem byla nalezena pozitivní korelace mezi hladinami cysteinu a homocysteinu (r = 0,506, p = 0,044), narozdíl od pacientů se stenózou (r = 0,056, p = 0,8287). Prevalence poměru cystein/homocystein, menším než 25, byla (cs)
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| Title
| - The relationship between homocysteine and cysteine in patients with different angiographic findings
- The relationship between homocysteine and cysteine in patients with different angiographic findings (en)
- Vztah mezi homocysteinem a cysteinem u pacientů s různými angiografickými nálezy (cs)
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| skos:prefLabel
| - The relationship between homocysteine and cysteine in patients with different angiographic findings
- The relationship between homocysteine and cysteine in patients with different angiographic findings (en)
- Vztah mezi homocysteinem a cysteinem u pacientů s různými angiografickými nálezy (cs)
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| skos:notation
| - RIV/00216275:25310/07:00006515!RIV08-MSM-25310___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216275:25310/07:00006515
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - homocysteine; cysteine; liquid chromatography with electrochemical detection; angiographic findings (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...i/riv/nazevZdroje
| - Clinical Chemistry and Laboratory Medicine
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Kanďár, Roman
- Žáková, Pavla
- Vojtíšek, Petr
- Myjavec, Andrej
- Stoklasová, Martina
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://purl.org/ne...btex#hasPublisher
| - Walter de Gruyter GmbH & Co. KG
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| http://localhost/t...ganizacniJednotka
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