About: Oxidative stress and inflammatory markers in advanced coronary artery disease

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Oxidační stres a zánětlivé markery u pokročilého onemocnění koronárních tepen (cs) Background. The disbalance of redox equilibrium and chronic inflammatory status play a role in pathophysiology of atherosclerosis. The aim was to asses the impact of systemic inflammation, oxidative stress and antioxidative status in patients with advanced coronary artery disease. Methods. Inflammatory and oxidative stress parameters were determined in group of patients with serious coronary artery disease (at least 50% stenosis of the left main coronary artery or 70% stenosis of other coronary artery according to coronarographic examination; S, n=40) and control group of healthy people (C, n=48). Total amount of free radicals was determined by spectrophotometric assay; malondialdehyde, glutathione, homocysteine and alpha-tocopherol plasma concentrations by HPLC. Plasma levels of hsCRP, alpha1antiproteinase, total cholesterol, triglycerides, HDL-ch, LDL-ch, albumin, fibrinogen were monitored. Results. In patients with coronary stenosis (S) higher level of free radicals (FR) coincided with higher Background. The disbalance of redox equilibrium and chronic inflammatory status play a role in pathophysiology of atherosclerosis. The aim was to asses the impact of systemic inflammation, oxidative stress and antioxidative status in patients with advanced coronary artery disease. Methods. Inflammatory and oxidative stress parameters were determined in group of patients with serious coronary artery disease (at least 50% stenosis of the left main coronary artery or 70% stenosis of other coronary artery according to coronarographic examination; S, n=40) and control group of healthy people (C, n=48). Total amount of free radicals was determined by spectrophotometric assay; malondialdehyde, glutathione, homocysteine and alpha-tocopherol plasma concentrations by HPLC. Plasma levels of hsCRP, alpha1antiproteinase, total cholesterol, triglycerides, HDL-ch, LDL-ch, albumin, fibrinogen were monitored. Results. In patients with coronary stenosis (S) higher level of free radicals (FR) coincided with higher (en)
Title	Oxidative stress and inflammatory markers in advanced coronary artery disease Oxidative stress and inflammatory markers in advanced coronary artery disease (en) Oxidační stres a zánětlivé markery u pokročilého onemocnění koronárních tepen (cs)
skos:prefLabel	Oxidative stress and inflammatory markers in advanced coronary artery disease Oxidative stress and inflammatory markers in advanced coronary artery disease (en) Oxidační stres a zánětlivé markery u pokročilého onemocnění koronárních tepen (cs)
skos:notation	RIV/00216275:25310/07:00006173!RIV08-MSM-25310___
http://linked.open.../vavai/riv/strany	S43-S44
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OC 124), Z(MSM0021627502)
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Roušar, Tomáš Kanďár, Roman Meloun, Milan Mužáková, Vladimíra Žáková, Pavla
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Pardubice / Fakulta chemicko-technologická
http://linked.open...dnocenehoVysledku	440391
http://linked.open...ai/riv/idVysledku	RIV/00216275:25310/07:00006173
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Oxidative stress; inflammation; coronary artery disease (en)
http://linked.open.../riv/klicoveSlovo	coronary artery disease Oxidative stress inflammation
http://linked.open...ontrolniKodProRIV	[9DCB15C0621C]
http://linked.open...i/riv/mistoVydani	London
http://linked.open...i/riv/nazevZdroje	Free Radical Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/OC%20124
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Kanďár, Roman Roušar, Tomáš Skalický, Jiří Meloun, Milan Žáková, Pavla Vojtíšek, Petr Mužáková, Vladimíra Kovařík, Jakub
http://linked.open...n/vavai/riv/zamer	Pokročilé analytické a separační metody a jejich aplikace v diagnostice a technologii živých a neživých materiálů
issn	1071-5762
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Informa Healthcare UK
http://localhost/t...ganizacniJednotka	25310

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