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| rdf:type
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| Description
| - Eight water-soluble 1,1-dimethylvanadocene amino acid complexes have been prepared via the reaction of (MeCp)2VCl2 (2) with one equivalent of amino acid (aa) in water affording [(MeCp)2V(aa)]Cl, where aa is glycine (3), L-alanine (4), L-valine (5), L-leucine (6), L-isoleucine (7), L-phenylalanine (8), L-histidine (9) and L-tryptophane (10). All prepared complexes have been characterized by EPR, IR and Raman spectroscopy, elemental analysis and mass spectrometry. Molecular structures of [(MeCp)2V(ala)]BPh4*CH3OH (11), [(MeCp)2V(leu)]PF6 (12) and [(MeCp)2V(ile)]PF6 (13) were determined by X-ray diffraction analysis. Cytotoxic properties of complexes 2-10 were investigated toward Escherichia coli B and compared with analogical unsubstituted vanadocene compounds (1, 14-21). The results showed that 1,1-dimethylvanadocene amino acid complexes have identical or slightly higher antiproliferative activity then their unsubstituted analogs.
- Eight water-soluble 1,1-dimethylvanadocene amino acid complexes have been prepared via the reaction of (MeCp)2VCl2 (2) with one equivalent of amino acid (aa) in water affording [(MeCp)2V(aa)]Cl, where aa is glycine (3), L-alanine (4), L-valine (5), L-leucine (6), L-isoleucine (7), L-phenylalanine (8), L-histidine (9) and L-tryptophane (10). All prepared complexes have been characterized by EPR, IR and Raman spectroscopy, elemental analysis and mass spectrometry. Molecular structures of [(MeCp)2V(ala)]BPh4*CH3OH (11), [(MeCp)2V(leu)]PF6 (12) and [(MeCp)2V(ile)]PF6 (13) were determined by X-ray diffraction analysis. Cytotoxic properties of complexes 2-10 were investigated toward Escherichia coli B and compared with analogical unsubstituted vanadocene compounds (1, 14-21). The results showed that 1,1-dimethylvanadocene amino acid complexes have identical or slightly higher antiproliferative activity then their unsubstituted analogs. (en)
- Eight water-soluble 1,1-dimethylvanadocene amino acid complexes have been prepared via the reaction of (MeCp)2VCl2 (2) with one equivalent of amino acid (aa) in water affording [(MeCp)2V(aa)]Cl, where aa is glycine (3), L-alanine (4), L-valine (5), L-leucine (6), L-isoleucine (7), L-phenylalanine (8), L-histidine (9) and L-tryptophane (10). All prepared complexes have been characterized by EPR, IR and Raman spectroscopy, elemental analysis and mass spectrometry. Molecular structures of [(MeCp)2V(ala)]BPh4*CH3OH (11), [(MeCp)2V(leu)]PF6 (12) and [(MeCp)2V(ile)]PF6 (13) were determined by X-ray diffraction analysis. Cytotoxic properties of complexes 2-10 were investigated toward Escherichia coli B and compared with analogical unsubstituted vanadocene compounds (1, 14-21). The results showed that 1,1-dimethylvanadocene amino acid complexes have identical or slightly higher antiproliferative activity then their unsubstituted analogs. (cs)
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| Title
| - 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B
- 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B (en)
- 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B (cs)
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| skos:prefLabel
| - 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B
- 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B (en)
- 1,1-Dimethylvanadocene -amino acid complexes: synthesis, characterization and antimicrobial behavior toward Escherichia coli B (cs)
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| skos:notation
| - RIV/00216275:25310/06:00004373!RIV07-MSM-25310___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216275:25310/06:00004373
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - bent metallocene; antitumor agents; 1; 1-dimethylvanadocene dichloride; X-ray structural analysis; EPR spectroscopy; Escherichia coli (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Applied Organometallic Chemistry
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
| |
| http://linked.open...iv/tvurceVysledku
| - Císařová, Ivana
- Erben, Milan
- Frumarová, Božena
- Holubová, Jana
- Vinklárek, Jaromír
- Paláčková, Hana
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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