About: Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia     Goto   Sponge   NotDistinct   Permalink

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Description
  • Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brain to inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or %22gate%22, irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas.
  • Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brain to inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or %22gate%22, irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas. (en)
Title
  • Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia
  • Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia (en)
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  • Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia
  • Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia (en)
skos:notation
  • RIV/00216224:14740/14:00079334!RIV15-MSM-14740___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED1.1.00/02.0068), P(LH11032)
http://linked.open...iv/cisloPeriodika
  • July
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  • 44476
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  • RIV/00216224:14740/14:00079334
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  • event-related potential; information overload; inhibition; P50 wave; schizophrenia; splitting (en)
http://linked.open.../riv/klicoveSlovo
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  • NZ - Nový Zéland
http://linked.open...ontrolniKodProRIV
  • [485803F3B278]
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  • NEUROPSYCHIATRIC DISEASE AND TREATMENT
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  • 10
http://linked.open...iv/tvurceVysledku
  • Bob, Petr
  • Raboch, Jiří
  • Vlček, Přemysl
http://linked.open...ain/vavai/riv/wos
  • 000339065100001
issn
  • 1178-2021
number of pages
http://bibframe.org/vocab/doi
  • 10.2147/NDT.S64219
http://localhost/t...ganizacniJednotka
  • 14740
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