About: The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients     Goto   Sponge   NotDistinct   Permalink

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Description
  • Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. While the absence of neurological “cerebellar signs” in most dystonia patients may be considered at least provoking, there are more subtle indications of cerebellar dysfunction in complex, demanding tasks. Specifically, given the role of the cerebellum in the neural representation of time, in the millisecond range, dysfunction to this structure is considered to be of greater importance than dysfunction of the basal ganglia. In the current study,we investigated the performance of cervical dystonia patients on a computer task known to engage the cerebellum, namely, the interception of a moving target with changing parameters (speed, acceleration, and angle) with a simple response (pushing a button).
  • Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. While the absence of neurological “cerebellar signs” in most dystonia patients may be considered at least provoking, there are more subtle indications of cerebellar dysfunction in complex, demanding tasks. Specifically, given the role of the cerebellum in the neural representation of time, in the millisecond range, dysfunction to this structure is considered to be of greater importance than dysfunction of the basal ganglia. In the current study,we investigated the performance of cervical dystonia patients on a computer task known to engage the cerebellum, namely, the interception of a moving target with changing parameters (speed, acceleration, and angle) with a simple response (pushing a button). (en)
Title
  • The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients
  • The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients (en)
skos:prefLabel
  • The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients
  • The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients (en)
skos:notation
  • RIV/00216224:14740/13:00065632!RIV14-MZ0-14740___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED1.1.00/02.0068), P(NT13437)
http://linked.open...iv/cisloPeriodika
  • Oct
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 87033
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14740/13:00065632
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cervical dystonia; cerebellar signs; basal ganglia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C046B3416C20]
http://linked.open...i/riv/nazevZdroje
  • Neural Plasticity
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • Neuveden
http://linked.open...iv/tvurceVysledku
  • Bareš, Martin
  • Kašpárek, Tomáš
  • Lungu, Ovidiu V.
  • Shaw, Daniel Joel
  • Filip, Pavel
http://linked.open...ain/vavai/riv/wos
  • 000325567500001
issn
  • 2090-5904
number of pages
http://bibframe.org/vocab/doi
  • 10.1155/2013/908741
http://localhost/t...ganizacniJednotka
  • 14740
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