About: The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent

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About: The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ncbi.nlm.nih.gov/pubmed/22002597
Description	Disturbances in the default mode network (DMN) have been described in many neurological and psychiatric disorders including Parkinson's disease (PD). The DMN is characterized by basal activity that increases during rest or passive visual fixation and decreases (%22deactivates'') during cognitive tasks. The network is believed to be involved in cognitive processes. We examined the DMN in PD patients on dopaminergic medication with normal cognitive performance compared to age-and gender-matched healthy controls (HC) using fMRI and three methodological procedures: independent component analysis of resting-state data, analysis of deactivation during a complex visual scene-encoding task, and seed-based functional connectivity analysis. In the PD group, we also studied the effect of dopaminergic medication on the DMN integrity. Disturbances in the default mode network (DMN) have been described in many neurological and psychiatric disorders including Parkinson's disease (PD). The DMN is characterized by basal activity that increases during rest or passive visual fixation and decreases (%22deactivates'') during cognitive tasks. The network is believed to be involved in cognitive processes. We examined the DMN in PD patients on dopaminergic medication with normal cognitive performance compared to age-and gender-matched healthy controls (HC) using fMRI and three methodological procedures: independent component analysis of resting-state data, analysis of deactivation during a complex visual scene-encoding task, and seed-based functional connectivity analysis. In the PD group, we also studied the effect of dopaminergic medication on the DMN integrity. (en)
Title	The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent (en)
skos:prefLabel	The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent (en)
skos:notation	RIV/00216224:14740/12:00064606!RIV13-MSM-14740___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	129827
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/12:00064606
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Parkinson's disease; Default mode network; Deactivation; Functional connectivity; Hippocampus; Levodopa (en)
http://linked.open.../riv/klicoveSlovo	Parkinson's disease Deactivation Default mode network Functional connectivity Hippocampus Levodopa
http://linked.open...odStatuVydavatele	AT - Rakouská republika
http://linked.open...ontrolniKodProRIV	[3AD6D000F128]
http://linked.open...i/riv/nazevZdroje	Journal of Neural Transmission
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	119
http://linked.open...iv/tvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open...ain/vavai/riv/wos	000302423900005
issn	0300-9564
number of pages	12 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00702-011-0723-5
http://localhost/t...ganizacniJednotka	14740

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