About: Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia     Goto   Sponge   NotDistinct   Permalink

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Description
  • Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing.
  • Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. (en)
Title
  • Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia
  • Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia (en)
skos:prefLabel
  • Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia
  • Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia (en)
skos:notation
  • RIV/00216224:14740/12:00064605!RIV13-MSM-14740___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika
  • 1-4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 129826
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14740/12:00064605
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  • Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [4690AF6A614F]
http://linked.open...i/riv/nazevZdroje
  • Neurodegenerative Diseases
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 10
http://linked.open...iv/tvurceVysledku
  • Rektorová, Irena
  • Mikl, Michal
  • Mareček, Radek
  • Krajčovičová, Lenka
http://linked.open...ain/vavai/riv/wos
  • 000303660600049
http://linked.open...n/vavai/riv/zamer
issn
  • 1660-2854
number of pages
http://bibframe.org/vocab/doi
  • 10.1159/000334765
http://localhost/t...ganizacniJednotka
  • 14740
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