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rdf:type
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Description
| - Colorectal cancer (CRC) is one of the most common types of cancers in the Czech Republic and it is the third leading cause of cancer-related death in the Western countries. The main reasons of high mortality are diagnosis at the stage of advanced disease, insufficient clinical classification and low level of therapy individualization associated with unsatisfactory therapy responses. That is the reason why several efforts have been made to find new biomarkers in CRC enabling early diagnosis of asymptomatic disease, accurate differentiation between particular clinical stages and individualization of the therapy. MicroRNAs (miRNAs) are small, non-coding, single-stranded RNAs, 18 25 nucleotides in length, that are endogenously expressed and post-transcriptionally regulate gene expression.
- Colorectal cancer (CRC) is one of the most common types of cancers in the Czech Republic and it is the third leading cause of cancer-related death in the Western countries. The main reasons of high mortality are diagnosis at the stage of advanced disease, insufficient clinical classification and low level of therapy individualization associated with unsatisfactory therapy responses. That is the reason why several efforts have been made to find new biomarkers in CRC enabling early diagnosis of asymptomatic disease, accurate differentiation between particular clinical stages and individualization of the therapy. MicroRNAs (miRNAs) are small, non-coding, single-stranded RNAs, 18 25 nucleotides in length, that are endogenously expressed and post-transcriptionally regulate gene expression. (en)
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Title
| - Identification and functional analysis of microRNA deregulated in colorectal cancer
- Identification and functional analysis of microRNA deregulated in colorectal cancer (en)
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skos:prefLabel
| - Identification and functional analysis of microRNA deregulated in colorectal cancer
- Identification and functional analysis of microRNA deregulated in colorectal cancer (en)
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skos:notation
| - RIV/00216224:14740/12:00062178!RIV13-MZ0-14740___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(ED1.1.00/02.0068), P(NT13549)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14740/12:00062178
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - microRNAs; oncology; colorectal cancer; DLD-1; HCT-116 (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Radová, Lenka
- Slabý, Ondřej
- Svoboda, Marek
- Vyzula, Rostislav
- Faltejsková, Petra
- Bešše, Andrej
- Mlčochová, Jitka
- Šrůtová, Klára
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http://localhost/t...ganizacniJednotka
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