About: The use of an internal standard extends the linear range of the SALDI MS analyses

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.ce-ce.org/cece2012/Proceedings%20CECE%202012%20Final+late%20abstracts_web.pdf
Description	Surface-assisted laser desorption/ionization mass spectrometry (SALDI MS) employing gold nanoparticles (Au NPs) has been presented as a useful method for the both qualitative and quantitative analysis of low molecular weight analytes. Besides the well-known benefit, such as the improvement in the analysis precision, the use of an internal standard was observed to extend the linear range of SALDI MS. Without the use of the internal standard, the linear range is presumably limited by the saturation of the Au NP surface where the desorption process takes place: at higher analyte concentration, an imperfect, multilayer assembly is formed leading to inefficient desorption and/or ionization and thus to reduced linearity and poor reproducibility. Surface-assisted laser desorption/ionization mass spectrometry (SALDI MS) employing gold nanoparticles (Au NPs) has been presented as a useful method for the both qualitative and quantitative analysis of low molecular weight analytes. Besides the well-known benefit, such as the improvement in the analysis precision, the use of an internal standard was observed to extend the linear range of SALDI MS. Without the use of the internal standard, the linear range is presumably limited by the saturation of the Au NP surface where the desorption process takes place: at higher analyte concentration, an imperfect, multilayer assembly is formed leading to inefficient desorption and/or ionization and thus to reduced linearity and poor reproducibility. (en)
Title	The use of an internal standard extends the linear range of the SALDI MS analyses The use of an internal standard extends the linear range of the SALDI MS analyses (en)
skos:prefLabel	The use of an internal standard extends the linear range of the SALDI MS analyses The use of an internal standard extends the linear range of the SALDI MS analyses (en)
skos:notation	RIV/00216224:14740/12:00057868!RIV13-GA0-14740___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GAP206/12/0538), S
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Tomalová, Iva Preisler, Jan
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	176315
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/12:00057868
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	SALDI MS; nanoparticles; internal standard (en)
http://linked.open.../riv/klicoveSlovo	nanoparticles SALDI MS internal standard
http://linked.open...ontrolniKodProRIV	[9A548FA45BB3]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno
http://linked.open...i/riv/nazevZdroje	CECE 2012
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel front-end strategies for desorption mass spectrometry Central european institute of technology
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Chang, Huan-Tsung Preisler, Jan Tomalová, Iva
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2012-01-01 (xsd:date)
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	9th International Interdisciplinary Meeting on Bioanalysis, CECE 2012
https://schema.org/isbn	9788090495913
http://localhost/t...ganizacniJednotka	14740

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