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  • Multistep phosphorelay (MSP) pathways mediate a wide spectrum of adaptive responses in plants, including hormonal and abiotic stress regulations. Recent genetic evidence suggests both partial redundancy and possible functional cross-talk on the one hand and a certain level of specificity on the other. Here, we discuss recent achievements improving our understanding of possible molecular mechanisms of specificity in MSP. We consider a certain evolutionary conservation of ancestral two-component signalling systems from bacteria in a process of molecular recognition that, as we have recently shown, could be applied also to a certain extent in the case of plant MSP. Furthermore, we discuss possible roles of kinase and phosphatase activities, kinetics of both these enzymatic reactions, and phosphorylation lifetime.
  • Multistep phosphorelay (MSP) pathways mediate a wide spectrum of adaptive responses in plants, including hormonal and abiotic stress regulations. Recent genetic evidence suggests both partial redundancy and possible functional cross-talk on the one hand and a certain level of specificity on the other. Here, we discuss recent achievements improving our understanding of possible molecular mechanisms of specificity in MSP. We consider a certain evolutionary conservation of ancestral two-component signalling systems from bacteria in a process of molecular recognition that, as we have recently shown, could be applied also to a certain extent in the case of plant MSP. Furthermore, we discuss possible roles of kinase and phosphatase activities, kinetics of both these enzymatic reactions, and phosphorylation lifetime. (en)
Title
  • Molecular Mechanisms of Signalling Specificity via Phosphorelay Pathways in Arabidopsis
  • Molecular Mechanisms of Signalling Specificity via Phosphorelay Pathways in Arabidopsis (en)
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  • Molecular Mechanisms of Signalling Specificity via Phosphorelay Pathways in Arabidopsis
  • Molecular Mechanisms of Signalling Specificity via Phosphorelay Pathways in Arabidopsis (en)
skos:notation
  • RIV/00216224:14740/11:00050115!RIV12-GA0-14740___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED1.1.00/02.0068), P(GA521/09/1699), P(GAP305/11/0756), P(LC06034), Z(MSM0021622415)
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  • 2
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  • 213500
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  • RIV/00216224:14740/11:00050115
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  • Arabidopsis thaliana; cytokinin; phosphorelay; plant hormone; signal integration; signal specificity; signalling pathway; two-component system (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AE - Stát Spojené arabské emiráty
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  • [981CCB87CE7F]
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  • CURRENT PROTEIN & PEPTIDE SCIENCE
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  • 12
http://linked.open...iv/tvurceVysledku
  • Hejátko, Jan
  • Horák, Jakub
  • Janda, Lubomír
  • Pekárová, Blanka
http://linked.open...ain/vavai/riv/wos
  • 000291109700007
http://linked.open...n/vavai/riv/zamer
issn
  • 1389-2037
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  • 14740
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