About: From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://omicsonline.org/open-access/from-endothelial-progenitor-cells-tissue-engineering-2157-7633.1000185.php?aid=24407
Description	Cardiovascular disease has become the leading cause of death in high income countries worldwide and the available treatment is not able to provide a complete recovery. Tissue engineering offers a possibility to construct autologous vein replacements for surgery. In this review we summarize approaches leading to artificial vascular graft construction. We discuss biomaterials currently in use, various drug delivery systems and the most appropriate cell cultures for vein engineering. Despite the progress in biomaterials and drug delivery systems, generating a suitable tissue microenvironment and selection of the appropriate cell population for graft seeding remains a major challenge. Here we focus on endothelial progenitor stem cells as the most suitable cell type for vascular graft construction. We discuss its sources, isolation techniques and differentiation procedures. Cardiovascular disease has become the leading cause of death in high income countries worldwide and the available treatment is not able to provide a complete recovery. Tissue engineering offers a possibility to construct autologous vein replacements for surgery. In this review we summarize approaches leading to artificial vascular graft construction. We discuss biomaterials currently in use, various drug delivery systems and the most appropriate cell cultures for vein engineering. Despite the progress in biomaterials and drug delivery systems, generating a suitable tissue microenvironment and selection of the appropriate cell population for graft seeding remains a major challenge. Here we focus on endothelial progenitor stem cells as the most suitable cell type for vascular graft construction. We discuss its sources, isolation techniques and differentiation procedures. (en)
Title	From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come? From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come? (en)
skos:prefLabel	From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come? From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come? (en)
skos:notation	RIV/00216224:14330/14:00073592!RIV15-GA0-14330___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GBP302/12/G157)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Madarásová, Martina Šalingová, Barbara Stejskal, Stanislav Šimara, Pavel Krontorád Koutná, Irena Tesařová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Fakulta informatiky
http://linked.open...dnocenehoVysledku	17552
http://linked.open...ai/riv/idVysledku	RIV/00216224:14330/14:00073592
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	EPC; In vitro vascularization; Small-diameter vessels (en)
http://linked.open.../riv/klicoveSlovo	In vitro vascularization Small-diameter vessels EPC
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1F6F5B21E37C]
http://linked.open...i/riv/nazevZdroje	Journal of Stem Cell Research & Therapy
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Conditions
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	4
http://linked.open...iv/tvurceVysledku	Stejskal, Stanislav Šimara, Pavel Krontorád Koutná, Irena Tesařová, Lenka Madarásová, Martina Šalingová, Barbara
issn	2157-7633
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.4172/2157-7633.1000185
http://localhost/t...ganizacniJednotka	14330

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