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  • The current interest in systems biology is to gain a better understanding of how the complex dynamic behaviour of the cell emerges from mutual interactions of molecular species. When solving such a nontrivial goal, biological data have to be necessarily integrated with mathematical modelling and computer analysis. Since the key aspect of biological modelling is based on unifying several kinds of data captured in terms of large-scale biological networks, scalable and automatized methods are necessary to obtain novel predictions and understanding. In this review, we provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models.
  • The current interest in systems biology is to gain a better understanding of how the complex dynamic behaviour of the cell emerges from mutual interactions of molecular species. When solving such a nontrivial goal, biological data have to be necessarily integrated with mathematical modelling and computer analysis. Since the key aspect of biological modelling is based on unifying several kinds of data captured in terms of large-scale biological networks, scalable and automatized methods are necessary to obtain novel predictions and understanding. In this review, we provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models. (en)
Title
  • High-performance analysis of biological systems dynamics with the DiVinE model checker
  • High-performance analysis of biological systems dynamics with the DiVinE model checker (en)
skos:prefLabel
  • High-performance analysis of biological systems dynamics with the DiVinE model checker
  • High-performance analysis of biological systems dynamics with the DiVinE model checker (en)
skos:notation
  • RIV/00216224:14330/10:00043826!RIV11-GA0-14330___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA201/09/1389), P(GP201/09/P497), S, Z(MSM0021622419)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 261585
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14330/10:00043826
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • molecular interaction networks; mathematical modeling and computer simulation; kinetic models; discrete abstraction; high-performance computing; model checking (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [3B412D105A17]
http://linked.open...i/riv/nazevZdroje
  • Briefings in Bioinformatics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 11
http://linked.open...iv/tvurceVysledku
  • Barnat, Jiří
  • Brim, Luboš
  • Šafránek, David
http://linked.open...ain/vavai/riv/wos
  • 00027798530
http://linked.open...n/vavai/riv/zamer
issn
  • 1467-5463
number of pages
http://localhost/t...ganizacniJednotka
  • 14330
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