About: Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry

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About: Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Image cytometry still faces the problem of the quality of cell image analysis results. Degradations caused by cell preparation, optics and electronics considerably affect most 2D and 3D cell image data acquired using optical microscopy. That is why image processing algorithms applied to these data typically offer imprecise and unreliable results. We have created a toolbox that can generate 3D digital phantoms of specific cellular components along with their corresponding images degraded by specific optics and electronics. The user can then apply image analysis methods to such simulated image data. The analysis results can be compared with ground truth derived from input object digital phantoms. In this way, image analysis methods can be compared to each other and their quality can be computed. We have also evaluated the plausibility of the synthetic images, measured by their similarity to real image data. Image cytometry still faces the problem of the quality of cell image analysis results. Degradations caused by cell preparation, optics and electronics considerably affect most 2D and 3D cell image data acquired using optical microscopy. That is why image processing algorithms applied to these data typically offer imprecise and unreliable results. We have created a toolbox that can generate 3D digital phantoms of specific cellular components along with their corresponding images degraded by specific optics and electronics. The user can then apply image analysis methods to such simulated image data. The analysis results can be compared with ground truth derived from input object digital phantoms. In this way, image analysis methods can be compared to each other and their quality can be computed. We have also evaluated the plausibility of the synthetic images, measured by their similarity to real image data. (en)
Title	Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry (en)
skos:prefLabel	Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry (en)
skos:notation	RIV/00216224:14330/09:00034932!RIV10-MSM-14330___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(2B06052), P(LC535)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kozubek, Michal Svoboda, David Stejskal, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Fakulta informatiky
http://linked.open...dnocenehoVysledku	316096
http://linked.open...ai/riv/idVysledku	RIV/00216224:14330/09:00034932
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	digital phantom; synthetic image; procedural texture; point spread function; fluorescence optical microscope; 3D image cytometry (en)
http://linked.open.../riv/klicoveSlovo	3D image cytometry fluorescence optical microscope procedural texture point spread function digital phantom synthetic image
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7A0D1EBEB139]
http://linked.open...i/riv/nazevZdroje	Cytometry Part A
http://linked.open...in/vavai/riv/obor	JD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	75A
http://linked.open...iv/tvurceVysledku	Svoboda, David Kozubek, Michal Stejskal, Stanislav
http://linked.open...ain/vavai/riv/wos	000266470100003
issn	1552-4922
number of pages	16 (xsd:int)
http://localhost/t...ganizacniJednotka	14330

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