About: Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We studied the cellular localization and colocalization of proteins AIF, endonuclease G and AMID, which were previously found to be involved in caspase-independent apoptosis. We designed mammalian expression vectors, which carry genes encoding the proteins of interest fused to the fluorescent proteins to study cellular localization and colocalization of these proteins. We predicted the cellular localization of the proteins of interest using software, which analyses the aminoacid sequence of the protein with various algorithms. We also designed and applied a novel method of single-cell image analysis of the translocation of the fluorescent proteins into the nucleus. Using the listed methods, we managed to confirm by software prediction the localization of AIF and endoG to mitochondria. We studied the cellular localization and colocalization of proteins AIF, endonuclease G and AMID, which were previously found to be involved in caspase-independent apoptosis. We designed mammalian expression vectors, which carry genes encoding the proteins of interest fused to the fluorescent proteins to study cellular localization and colocalization of these proteins. We predicted the cellular localization of the proteins of interest using software, which analyses the aminoacid sequence of the protein with various algorithms. We also designed and applied a novel method of single-cell image analysis of the translocation of the fluorescent proteins into the nucleus. Using the listed methods, we managed to confirm by software prediction the localization of AIF and endoG to mitochondria. (en)
Title	Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells (en)
skos:prefLabel	Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells Single-cell image analysis of cellular localization and colocalization of endonuclease G, AIF and AMID in living cells (en)
skos:notation	RIV/00216224:14330/06:00020052!RIV11-GA0-14330___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA202/04/0907), P(GP204/03/D031), P(GP204/05/P090), Z(MSM0021622419)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Amrichová, Jana Ulman, Vladimír Vařecha, Miroslav Kozubek, Michal Matula, Pavel Matula, Petr Zimmermann, Michal
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Fakulta informatiky
http://linked.open...dnocenehoVysledku	499499
http://linked.open...ai/riv/idVysledku	RIV/00216224:14330/06:00020052
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	living cells; image analysis; colocalization; fluorescent proteins; apoptosis (en)
http://linked.open.../riv/klicoveSlovo	living cells colocalization image analysis apoptosis fluorescent proteins
http://linked.open...ontrolniKodProRIV	[0DC7016098D5]
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	High-resolution cytomery of living cells Apoptosis-inducing factor (AIF): its translocation from mitochondria and its action on nuclear chromatin Topographic and functional characterization of telomeres in various tumor cell lines determined in situ and in vivo
http://linked.open...UplatneniVysledku	2006
http://linked.open...iv/tvurceVysledku	Matula, Pavel Ulman, Vladimír Kozubek, Michal Matula, Petr Vařecha, Miroslav Zimmermann, Michal Amrichová, Jana
http://linked.open...n/vavai/riv/zamer	Highly Parallel and Distributed Computing Systems
http://localhost/t...ganizacniJednotka	14330

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software