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rdf:type
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Description
| - Thyroid hormones and retinoic acid (RA) are important modulators of growth, development, and differentiation. The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-RA caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. All-trans-RA (5 uM) had little or no effect on type II deiodinase, the enzyme which catalyzes the activation of thyroxine to 3,5,3'-triiodothyronine.
- Thyroid hormones and retinoic acid (RA) are important modulators of growth, development, and differentiation. The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-RA caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. All-trans-RA (5 uM) had little or no effect on type II deiodinase, the enzyme which catalyzes the activation of thyroxine to 3,5,3'-triiodothyronine. (en)
- Thyroid hormones and retinoic acid (RA) are important modulators of growth, development, and differentiation. The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-RA caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. All-trans-RA (5 uM) had little or no effect on type II deiodinase, the enzyme which catalyzes the activation of thyroxine to 3,5,3'-triiodothyronine. (cs)
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Title
| - Induction of type III-deiodinase activity in astroglial cells by retinoids
- Induction of type III-deiodinase activity in astroglial cells by retinoids (en)
- Induction of type III-deiodinase activity in astroglial cells by retinoids (cs)
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skos:prefLabel
| - Induction of type III-deiodinase activity in astroglial cells by retinoids
- Induction of type III-deiodinase activity in astroglial cells by retinoids (en)
- Induction of type III-deiodinase activity in astroglial cells by retinoids (cs)
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skos:notation
| - RIV/00216224:14310/94:00011186!RIV09-AV0-14310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/94:00011186
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Brain; cultured astrocytes; deiodinase; retinoic acid; thyroid hormones (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Glia [IF=5.096 (1993); SCI #cit.<35>]
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Pavelka, Stanislav
- Courtin, Francoise
- Esfandiari, Ali
- Gagelin, Claire
- Gavaret, Jean-Michel
- Lennon, Ana-Maria
- Pierre, Michel
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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