About: MALDI-TOF fingerprinting of the whole mammalian cell-lines

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Robust cell-lines identification requires reliable databases of cell-lines fingerprints. Mass spectrometric fingerprinting of mammalian cell-lines is a promising way to achieve the goal of fast, cheap, simple and reliable cell-lines authentication. However, general and standardized method for mass spectrometric fingerprinting of the whole mammalian cell-lines is not available to date. We developed, optimized and validated MALDI-TOF mass spectrometric method for reliable, specific and reproducible whole-cell fingerprinting of mammalian cell-lines. Quality and robustness of mass spectrometric fingerprints is demonstrated by statistical analysis of experimental data. Developed method for the whole mammalian cell-lines fingerprinting, in contrast to actual procedures, is inexpensive, fast and it opens the door towards routine cell authentication. Robust cell-lines identification requires reliable databases of cell-lines fingerprints. Mass spectrometric fingerprinting of mammalian cell-lines is a promising way to achieve the goal of fast, cheap, simple and reliable cell-lines authentication. However, general and standardized method for mass spectrometric fingerprinting of the whole mammalian cell-lines is not available to date. We developed, optimized and validated MALDI-TOF mass spectrometric method for reliable, specific and reproducible whole-cell fingerprinting of mammalian cell-lines. Quality and robustness of mass spectrometric fingerprints is demonstrated by statistical analysis of experimental data. Developed method for the whole mammalian cell-lines fingerprinting, in contrast to actual procedures, is inexpensive, fast and it opens the door towards routine cell authentication. (en)
Title	MALDI-TOF fingerprinting of the whole mammalian cell-lines MALDI-TOF fingerprinting of the whole mammalian cell-lines (en)
skos:prefLabel	MALDI-TOF fingerprinting of the whole mammalian cell-lines MALDI-TOF fingerprinting of the whole mammalian cell-lines (en)
skos:notation	RIV/00216224:14310/14:00078221!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0086), Z(MSM0021622411), Z(MSM0021622430)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kučera, Lukáš Havel, Josef Hampl, Aleš Vaňhara, Petr Amato, Filippo
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	27012
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00078221
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mammalian cell-lines; MALDI-TOF; mass spectrometry; fingerprinting (en)
http://linked.open.../riv/klicoveSlovo	mammalian cell-lines MALDI-TOF mass spectrometry fingerprinting
http://linked.open...ontrolniKodProRIV	[ABCCEC6CDC77]
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional R&D center for low-cost plasma and nanotechnology surface modifications
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Amato, Filippo Havel, Josef Hampl, Aleš Kučera, Lukáš Vaňhara, Petr
http://linked.open...n/vavai/riv/zamer	Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
http://localhost/t...ganizacniJednotka	14310

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