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  • In vitro assays are broadly used tools to evaluate the estrogenic activity in Waste Water Treatment Plant (WWTP) effluents and their receiving rivers. Since potencies of individual estrogens to induce in vitro and in vivo responses can differ it is not possible to directly evaluate risks based on in vitro measures of estrogenic activity. Estrone, 17beta-estradiol, 17alfa-ethinylestradiol and to some extent, estriol have been shown to be responsible for the majority of in vitro estrogenic activity of municipal WWTP effluents. Therefore, in the present study safe concentrations of Estrogenic Equivalents (EEQs-SSE) in municipal WWTP effluents were derived based on simplified assumption that the steroid estrogens are responsible for all estrogenicity determined with particular in vitro assays.
  • In vitro assays are broadly used tools to evaluate the estrogenic activity in Waste Water Treatment Plant (WWTP) effluents and their receiving rivers. Since potencies of individual estrogens to induce in vitro and in vivo responses can differ it is not possible to directly evaluate risks based on in vitro measures of estrogenic activity. Estrone, 17beta-estradiol, 17alfa-ethinylestradiol and to some extent, estriol have been shown to be responsible for the majority of in vitro estrogenic activity of municipal WWTP effluents. Therefore, in the present study safe concentrations of Estrogenic Equivalents (EEQs-SSE) in municipal WWTP effluents were derived based on simplified assumption that the steroid estrogens are responsible for all estrogenicity determined with particular in vitro assays. (en)
Title
  • What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe?
  • What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe? (en)
skos:prefLabel
  • What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe?
  • What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe? (en)
skos:notation
  • RIV/00216224:14310/14:00074427!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GAP503/12/0553)
http://linked.open...iv/cisloPeriodika
  • MAR 2014
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 56131
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/14:00074427
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Estrogen; Threshold; In vitro assay; Environmental risk assessment; Waste water treatment plant (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [18A67A36258F]
http://linked.open...i/riv/nazevZdroje
  • Environment International
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 64
http://linked.open...iv/tvurceVysledku
  • Bláha, Luděk
  • Hilscherová, Klára
  • Jarošová, Barbora
  • Giesy, J. P.
http://linked.open...ain/vavai/riv/wos
  • 000333512900012
issn
  • 0160-4120
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.envint.2013.12.009
http://localhost/t...ganizacniJednotka
  • 14310
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