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  • The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between selected 1st generation antidiabetic drugs (tolbutamide, chlorpropamide) and human serum albumin (HSA). The binding constant (Kb) was measured under physiological conditions. The log Kb values obtained by means of CE-FA have a good repeatability (RSD < 3%).
  • The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between selected 1st generation antidiabetic drugs (tolbutamide, chlorpropamide) and human serum albumin (HSA). The binding constant (Kb) was measured under physiological conditions. The log Kb values obtained by means of CE-FA have a good repeatability (RSD < 3%). (en)
Title
  • Determination of binding constant of 1st generation antidiabetic drug with human serum albumin
  • Determination of binding constant of 1st generation antidiabetic drug with human serum albumin (en)
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  • Determination of binding constant of 1st generation antidiabetic drug with human serum albumin
  • Determination of binding constant of 1st generation antidiabetic drug with human serum albumin (en)
skos:notation
  • RIV/00216224:14310/14:00074050!RIV15-GA0-14310___
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  • P(GBP206/12/G014)
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  • 10738
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  • RIV/00216224:14310/14:00074050
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  • capillary electrophoresis - frontal analysis; 1st generation anitiabetic drugs; HSA (en)
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  • [F4FE7EA1F055]
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  • Brno
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  • Brno
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  • 11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014
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  • Michalcová, Lenka
  • Glatz, Zdeněk
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  • Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika
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  • 9788090495920
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  • 14310
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