| Attributes | Values |
|---|
| rdf:type
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| Description
| - Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approaches have only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discussed.
- Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approaches have only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discussed. (en)
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| Title
| - A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment
- A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment (en)
|
| skos:prefLabel
| - A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment
- A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment (en)
|
| skos:notation
| - RIV/00216224:14310/13:00071493!RIV14-MSM-14310___
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| |
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/13:00071493
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - Cell lines; 3Rs; QSAR; Read-across; Exposure-based waiving; Fish embryo test; Acute toxicity; Chronic toxicity; Endocrine disruption; Bioconcentration (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - REGULATORY TOXICOLOGY AND PHARMACOLOGY
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Bláha, Luděk
- Scholz, Stefan
- Belanger, Scott
- Benfenati, Emilio
- Braunbeck, Thomas
- Creton, Stuart
- Cronin, Mark T D
- Eggen, Rik I L
- Ekman, Drew
- Embry, Michelle
- Galay-Burgos, Malyka
- Garcia-Franco, Mauricio
- Gourmelon, Anne
- Guinea, Joaquin
- Halder, Marlies
- Hardy, Barry
- Hartung, Thomas
- Hubesch, Bruno
- Jungmann, Dirk
- Kluever, Nils
- Kuester, Eberhard
- Lampi, Mark A
- Lee, Lucy
- Leonard, Marc
- Lillicrap, Adam
- Luckenbach, Till
- Murk, Albertinka J
- Navas, Jose M
- Peijnenburg, Willie
- Repetto, Guillermo
- Salinas, Edward
- Schirmer, Kristin
- Schueuermann, Gerrit
- Sela, Erika
- Spielmann, Horst
- Tanneberger, Katrin
- Tobor-Kaplon, Marysia
- Tollefsen, Knut Erik
- Walter-Rohde, Susanne
- Whale, Graham
- Wheeler, James R
- Winter, Matthew J
- Witters, Hilda
|
| http://linked.open...ain/vavai/riv/wos
| |
| issn
| |
| number of pages
| |
| http://bibframe.org/vocab/doi
| - 10.1016/j.yrtph.2013.10.003
|
| http://localhost/t...ganizacniJednotka
| |
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