About: Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Antineoplastic drugs are considered as a potential health risk to healthcare personnel, due to their adverse effects. The objective of the study was to compare the surface contamination level of the conventional preparation room and outpatient clinic before and after the implementation of a set of additional protective measures. To determine the surface contamination level with antineoplastic drugs, cyclophosphamide and platinum were determined in wipe samples with high performance liquid chromatography with tandem mass spectrometry and inductively coupled plasma mass spectrometry.In the preparation room, depending on the sampling spot and analyte, median concentrations ranged from 5 to 267 pg cm(2) and from 2 to 368 pg cm(2) before and after implementation of the measures, respectively. In the outpatient clinic, median concentrations ranged from 5 to 5310 pg cm(2) and from < 0.2 to 574 pg cm(2) before and after implementation of the measures, respectively. Antineoplastic drugs are considered as a potential health risk to healthcare personnel, due to their adverse effects. The objective of the study was to compare the surface contamination level of the conventional preparation room and outpatient clinic before and after the implementation of a set of additional protective measures. To determine the surface contamination level with antineoplastic drugs, cyclophosphamide and platinum were determined in wipe samples with high performance liquid chromatography with tandem mass spectrometry and inductively coupled plasma mass spectrometry.In the preparation room, depending on the sampling spot and analyte, median concentrations ranged from 5 to 267 pg cm(2) and from 2 to 368 pg cm(2) before and after implementation of the measures, respectively. In the outpatient clinic, median concentrations ranged from 5 to 5310 pg cm(2) and from < 0.2 to 574 pg cm(2) before and after implementation of the measures, respectively. (en)
Title	Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs (en)
skos:prefLabel	Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs (en)
skos:notation	RIV/00216224:14310/13:00067961!RIV14-MSM-14310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(2B06171), P(ED0001/01/01), P(ED2.1.00/03.0101), P(EE2.3.20.0053), P(LM2011028), S
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Piler, Pavel Bláha, Luděk Oravec, Michal Kuta, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	73678
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/13:00067961
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	chemical analysis; cytotoxic drugs; hazardous pharmaceuticals; occupational exposure; safety engineering (en)
http://linked.open.../riv/klicoveSlovo	chemical analysis safety engineering hazardous pharmaceuticals cytotoxic drugs occupational exposure
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B92A66B172FA]
http://linked.open...i/riv/nazevZdroje	ANNALS OF OCCUPATIONAL HYGIENE
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	RECETOX – National research infrastructure for toxic compounds in the environment Support of experts and international networking in environmental research in the Czech Republic Research of the occupational risk exposure of health care professionals handling with hazardous pharmaceuticals in long term sub and threshold expositions. CETOCOEN Regional Centre for Applied Molecular Oncology (RECAMO)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Odráška, Pavel Oravec, Michal Kuta, Jan Dolezalova, Lenka Piler, Pavel
http://linked.open...ain/vavai/riv/wos	000315158600008
issn	0003-4878
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1093/annhyg/mes057
http://localhost/t...ganizacniJednotka	14310

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