About: Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum

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About: Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Monogeneans of the family Diplozoidae are ectoparasitic blood-feeders inhabiting the gills of cyprinid fish. They can be significantly virulent to their hosts, causing mechanical damage to gill filaments accompanied by a risk of secondary bacterial and mycotic infections or anemia. In contrast to other blood-feeding parasites, the host-parasite %22communication%22 at the molecular level is among monogeneans largely unknown. We performed the first insights into molecular biology of diplozoid parasites by exploring the transcriptome of the adult stage of Eudiplozoon nipponicum (group Heteronchoinea), using 454 sequencing technology (GS FLX System, ROCHE). We are primarily focused on identification and characterization of selected molecules involved in host-parasite interaction. Special attention is paid to molecules participating on digestion of host's blood (e.g. proteolytic enzymes - peptidases) and other molecules (e.g. anticoagulants) playing essential role in biological processes in the parasite. Monogeneans of the family Diplozoidae are ectoparasitic blood-feeders inhabiting the gills of cyprinid fish. They can be significantly virulent to their hosts, causing mechanical damage to gill filaments accompanied by a risk of secondary bacterial and mycotic infections or anemia. In contrast to other blood-feeding parasites, the host-parasite %22communication%22 at the molecular level is among monogeneans largely unknown. We performed the first insights into molecular biology of diplozoid parasites by exploring the transcriptome of the adult stage of Eudiplozoon nipponicum (group Heteronchoinea), using 454 sequencing technology (GS FLX System, ROCHE). We are primarily focused on identification and characterization of selected molecules involved in host-parasite interaction. Special attention is paid to molecules participating on digestion of host's blood (e.g. proteolytic enzymes - peptidases) and other molecules (e.g. anticoagulants) playing essential role in biological processes in the parasite. (en)
Title	Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum (en)
skos:prefLabel	Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum Bioactive molecules of the blood-feeding monogenean Eudiplozoon nipponicum (en)
skos:notation	RIV/00216224:14310/13:00066899!RIV14-MSM-14310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GAP506/12/1258), S
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Kašný, Martin Ilgová, Jana Gelnar, Milan Koubková, Božena
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	63369
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/13:00066899
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Eudiplozoon nipponicum; host-parasite interaction; blood digestion; peptidases; inhibitors; molecules; transcriptome (en)
http://linked.open.../riv/klicoveSlovo	host-parasite interaction peptidases inhibitors molecules transcriptome Eudiplozoon nipponicum blood digestion
http://linked.open...ontrolniKodProRIV	[76443C1B894E]
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Host-parasite interactions in blood-feeding diplozoid monogeneans: Investigation of highly specialized adaptation for parasitism
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Koubková, Božena Kašný, Martin Mikeš, Libor Dvořáková, Hana Ilgová, Jana Gelnar, Milan Dzika, Ewa Jedličková, Lucie Skipalová, Karolína
http://localhost/t...ganizacniJednotka	14310

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