About: Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass

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About: Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	OBJECTIVES: Cyanobacteria are producers of potent and environmentally abundant microcystins, representing an emerging global health issue. In the present study, we investigated the impact of pure microcystins and cyanobacterial biomass on laboratory rats (Wistar albino rats, males, 30 days old) under different exposure scenarios. METHODS: The rats were fed diets containing fish meat with microcystins in various concentrations and forms (cyanobacterial biomass and isolated microcystins) for 28 days. RESULTS: Although considerable amounts of microcystins (MCs) were administered to the rats, all levels of MCs in the liver were close to the detection limit (3-5 ng/g fresh weight) using liquid chromatography - tandem mass spectrometry. OBJECTIVES: Cyanobacteria are producers of potent and environmentally abundant microcystins, representing an emerging global health issue. In the present study, we investigated the impact of pure microcystins and cyanobacterial biomass on laboratory rats (Wistar albino rats, males, 30 days old) under different exposure scenarios. METHODS: The rats were fed diets containing fish meat with microcystins in various concentrations and forms (cyanobacterial biomass and isolated microcystins) for 28 days. RESULTS: Although considerable amounts of microcystins (MCs) were administered to the rats, all levels of MCs in the liver were close to the detection limit (3-5 ng/g fresh weight) using liquid chromatography - tandem mass spectrometry. (en)
Title	Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass (en)
skos:prefLabel	Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass Biochemical and histopathological responses of Wistar rats to oral intake of microcystins and cyanobacterial biomass (en)
skos:notation	RIV/00216224:14310/13:00065693!RIV14-MZE-14310___
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(ED0001/01/01), P(QH71015), V, Z(MSM6215648905), Z(MSM6215712402)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Adamovský, Ondřej Bláha, Luděk Kohoutek, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	63377
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/13:00065693
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cyanobacteria; laboratory rats; experimental exposure; oxidative stress; biochemistry; histopathology (en)
http://linked.open.../riv/klicoveSlovo	experimental exposure laboratory rats biochemistry Cyanobacteria histopathology oxidative stress
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[CDDC9D85EF48]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	DJ
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	CETOCOEN Risk Minimization of Cyanobacterial Metabolite Occurrence in Technologic Processes of Fishery Sector
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	34
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Kopp, Radovan Mareš, Jan Paskerová, Hana Pikula, Jiří Kohoutek, Jiří Adamovský, Ondřej Palíková, Miroslava Ondrackova, Petra Zikova, Andrea
http://linked.open...ain/vavai/riv/wos	000330901000002
http://linked.open...n/vavai/riv/zamer	Biological and technological aspects of sustainability of controlled ecosystems and their adaptability to climate change Veterinary aspects of food safety and quality
issn	0172-780X
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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