About: Do cyanobacteria produce estrogenic compounds?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Do cyanobacteria produce estrogenic compounds? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Number of studies document hazardous potential of cyanobacterial metabolites.Despite the observed effects on reproduction related parameters, growth and development,there is little information on endocrine disruptive potential of compounds from cyanobacteria.Our research aimed to determine if complex water bloom of cyanobacteria collected from the environment contain compounds that would interact with the signaling pathways of arylhydrocarbon receptor (AhR), androgenic receptor (AR), estrogenic receptor (ER),glucocorticoid receptor (GR) or retinoid acid receptor (RAR).In vitro reporter gene trans-activation assays were used to determine the potency of samples to elicit receptor-mediated responses.Estrogenicity was detected for most environmental samples, their estimated estrogenic equivalents ranged from 19 to 2200 ng 17b-estradiol /g dw.Some of them also interfered with the signalling of androgen receptor. Number of studies document hazardous potential of cyanobacterial metabolites.Despite the observed effects on reproduction related parameters, growth and development,there is little information on endocrine disruptive potential of compounds from cyanobacteria.Our research aimed to determine if complex water bloom of cyanobacteria collected from the environment contain compounds that would interact with the signaling pathways of arylhydrocarbon receptor (AhR), androgenic receptor (AR), estrogenic receptor (ER),glucocorticoid receptor (GR) or retinoid acid receptor (RAR).In vitro reporter gene trans-activation assays were used to determine the potency of samples to elicit receptor-mediated responses.Estrogenicity was detected for most environmental samples, their estimated estrogenic equivalents ranged from 19 to 2200 ng 17b-estradiol /g dw.Some of them also interfered with the signalling of androgen receptor. (en)
Title	Do cyanobacteria produce estrogenic compounds? Do cyanobacteria produce estrogenic compounds? (en)
skos:prefLabel	Do cyanobacteria produce estrogenic compounds? Do cyanobacteria produce estrogenic compounds? (en)
skos:notation	RIV/00216224:14310/12:00067012!RIV14-MSM-14310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED0001/01/01), P(GAP503/12/0553), S
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Nováková, Kateřina Bláha, Luděk Hilscherová, Klára Štěpánková, Tereza Sychrová, Eliška
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	131776
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/12:00067012
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cyanobacteria; Estrogenic activity (en)
http://linked.open.../riv/klicoveSlovo	Estrogenic activity Cyanobacteria
http://linked.open...ontrolniKodProRIV	[A0E3F7EF8A69]
http://linked.open...in/vavai/riv/obor	DJ
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Endocrine disruptive potential of cyanobacterial metabolites CETOCOEN
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Hilscherová, Klára Nováková, Kateřina Štěpánková, Tereza Giesy, J .P. Sychrová, Eliška
http://localhost/t...ganizacniJednotka	14310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software