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Description
  • The identification of cancer stem cell markers represents one of the very relevant research topics because cancer stem cells play important roles in tumour initiation and progression, as well as during metastasis formation and in relapse of the disease. This article summarises recent knowledge on well-known and putative cancer stem cell markers in various types of bone and soft-tissue sarcomas. Special attention is paid to the detection of CD133, ABC transporters, nestin and aldehyde dehydrogenase that have been intensively studied both in tumour tissues and in sarcoma cell lines during the past few years. Finally, an overview is given of the possible CSC phenotypes provided by functional assays of tumourigenicity.
  • The identification of cancer stem cell markers represents one of the very relevant research topics because cancer stem cells play important roles in tumour initiation and progression, as well as during metastasis formation and in relapse of the disease. This article summarises recent knowledge on well-known and putative cancer stem cell markers in various types of bone and soft-tissue sarcomas. Special attention is paid to the detection of CD133, ABC transporters, nestin and aldehyde dehydrogenase that have been intensively studied both in tumour tissues and in sarcoma cell lines during the past few years. Finally, an overview is given of the possible CSC phenotypes provided by functional assays of tumourigenicity. (en)
Title
  • Detection of cancer stem cell markers in sarcomas
  • Detection of cancer stem cell markers in sarcomas (en)
skos:prefLabel
  • Detection of cancer stem cell markers in sarcomas
  • Detection of cancer stem cell markers in sarcomas (en)
skos:notation
  • RIV/00216224:14310/12:00065657!RIV14-MZ0-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED2.1.00/03.0101), P(NT13443)
http://linked.open...iv/cisloPeriodika
  • Suppl 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 130427
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/12:00065657
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cancer stem cells; osteosarcoma; rhabdomyosarcoma; CD133; ABC transporters; nestin; aldehyde dehydrogenase; tumourigenicity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [89DB8B69E4DA]
http://linked.open...i/riv/nazevZdroje
  • Klinická onkologie
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Neradil, Jakub
  • Veselská, Renata
  • Škoda, Jan
issn
  • 0862-495X
number of pages
http://localhost/t...ganizacniJednotka
  • 14310
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