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  • In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consists in modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5].
  • In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consists in modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5]. (en)
Title
  • Gold nanoparticles modified by thrombin binding aptamer
  • Gold nanoparticles modified by thrombin binding aptamer (en)
skos:prefLabel
  • Gold nanoparticles modified by thrombin binding aptamer
  • Gold nanoparticles modified by thrombin binding aptamer (en)
skos:notation
  • RIV/00216224:14310/11:00054375!RIV12-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC06035), S, Z(MSM0021622412)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 201410
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/11:00054375
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • AuNPs; TBA; SAM; DNA; TEM (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [CEC66ADF0F8F]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Castillo, Gabriela
  • Trnková, Libuše
  • Pilařová, Iveta
http://linked.open...n/vavai/riv/zamer
http://localhost/t...ganizacniJednotka
  • 14310
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