About: Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice.

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About: Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Mouse embryonic carcinoma cells (P19 line) were studied for both their survival and developmental potential in the intact cerebellum of B6CBA mice. The P19 cells were cultured and labelled with green fluorescent protein using transfection. Cells were used for transplantation either in the undifferentiated stage or after 3 days of neurodifferentiation induced by retinoic acid. The intracerebellar application was performed in 43 mice: group A (N = 21) received neuroprogenitors and group B (N = 22) received undifferentiated cells. The morphology of transplanted cells within the context of the surrounding cerebellar tissue was evaluated after 3 weeks. Naive P19 cells engrafted and survived in the cerebellum of 7 of the 22 adult mice (survival rate 31.8 %). Neuroprogenitors survived in 13 of the 21 mice (survival rate was 61.9 %). Since the cut-off is P < 0.05, the difference is not statistically significant (P = 0.069). An expansive appearance of the graft was significantly more frequent (P = 0. Mouse embryonic carcinoma cells (P19 line) were studied for both their survival and developmental potential in the intact cerebellum of B6CBA mice. The P19 cells were cultured and labelled with green fluorescent protein using transfection. Cells were used for transplantation either in the undifferentiated stage or after 3 days of neurodifferentiation induced by retinoic acid. The intracerebellar application was performed in 43 mice: group A (N = 21) received neuroprogenitors and group B (N = 22) received undifferentiated cells. The morphology of transplanted cells within the context of the surrounding cerebellar tissue was evaluated after 3 weeks. Naive P19 cells engrafted and survived in the cerebellum of 7 of the 22 adult mice (survival rate 31.8 %). Neuroprogenitors survived in 13 of the 21 mice (survival rate was 61.9 %). Since the cut-off is P < 0.05, the difference is not statistically significant (P = 0.069). An expansive appearance of the graft was significantly more frequent (P = 0. (en)
Title	Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice. Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice. (en)
skos:prefLabel	Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice. Comparison of P19-derived neuroprogenitor and naive cell survival after intracerebellar application into B6CBA mice. (en)
skos:notation	RIV/00216224:14310/11:00050508!RIV12-GA0-14310___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA301/08/0717), P(OC10038), S, Z(MSM0021620816)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Veselá, Iva Pacherník, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	191209
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/11:00050508
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	P19-derived neuroprogenitors; naive P19 cells; intracerebellar application; graft survival (en)
http://linked.open.../riv/klicoveSlovo	P19-derived neuroprogenitors graft survival intracerebellar application naive P19 cells
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[FD58420C91AD]
http://linked.open...i/riv/nazevZdroje	Folia Biol.
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Gp130 receptor-mediated differentiation of ES cells Transplantation of the embryonic cerebellar tissue and stem cells into the cerebellum of Lurcher mutant and normal mice
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Babuška, V. Cendelín, J. Hatina, J. Houdek, Zbyněk Králíčková, M. Kulda, V. Pacherník, Jiří Uher, P. Veselá, Iva Vožeh, F. Zech, N. H.
http://linked.open...ain/vavai/riv/wos	000295701300005
http://linked.open...n/vavai/riv/zamer	Název: Patofyziologie neuropsychiatrických onemocnění a její klinické aplikace
issn	0015-5500
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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