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  • The GDF-15 concentration in seminal plasma ranged from 0.2 to 6.6 ug/ml as determined by ELISA. Western blot analysis revealed that GDF-15 is present in the active form. In vitro cultivation of sperm cells with GDF-15 did not affect their viability or rates of apoptosis; however, it did inhibit proliferation of PBMCs and induce expression of FOXP3 in CD4+CD25+ cells.
  • The GDF-15 concentration in seminal plasma ranged from 0.2 to 6.6 ug/ml as determined by ELISA. Western blot analysis revealed that GDF-15 is present in the active form. In vitro cultivation of sperm cells with GDF-15 did not affect their viability or rates of apoptosis; however, it did inhibit proliferation of PBMCs and induce expression of FOXP3 in CD4+CD25+ cells. (en)
Title
  • Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma
  • Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma (en)
skos:prefLabel
  • Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma
  • Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma (en)
skos:notation
  • RIV/00216224:14310/10:00067238!RIV14-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NS9600), Z(AV0Z50040507), Z(AV0Z50040702), Z(AV0Z50390703), Z(MSM0021622430)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 261075
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/10:00067238
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Seminal plasma; Growth/Differentiation Factor 15 (GDF15/MIC1); FOXP3 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [D337F47F4C38]
http://linked.open...i/riv/nazevZdroje
  • Hum. Reprod.
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Hampl, Aleš
  • Kozubík, Alois
  • Ovesná, Petra
  • Slabáková, Eva
  • Souček, Karel
  • Malenovská, Alice
http://linked.open...ain/vavai/riv/wos
  • 000284637500008
http://linked.open...n/vavai/riv/zamer
issn
  • 0268-1161
number of pages
http://localhost/t...ganizacniJednotka
  • 14310
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