About: Association between major histocompatibility complex class IIB alleles and metazoan parasite load in populations of European chub (Leuciscus cephalus): testing of balancing selection     Goto   Sponge   NotDistinct   Permalink

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  • The genes of major histocompatibility complex (MHC), the most polymorphic loci known in vertebrates, have become the most studied genes in molecular ecology because they represent one of the best candidates suitable to study natural selection on a molecular level in the wild populations. The extremely high level of MHC allelic diversity is result of many mechanisms, especially the parasite-driven balancing selection, as well as recombination, gene duplication mutation and genetic drift. The main objectives of the present study were: a) to perform a sequence analysis of MHC class IIB alleles in European chub (Leuciscus cephalus), b) to investigate the contribution of evolutionary mechanisms (selection, recombination) to MHC diversity, and c) to analyse the co-evolutionary relationship between metazoan parasite load and MHC class IIB alleles. A total of 311 individuals from 15 populations of chub were collected from European rivers across a wide geographical range.
  • The genes of major histocompatibility complex (MHC), the most polymorphic loci known in vertebrates, have become the most studied genes in molecular ecology because they represent one of the best candidates suitable to study natural selection on a molecular level in the wild populations. The extremely high level of MHC allelic diversity is result of many mechanisms, especially the parasite-driven balancing selection, as well as recombination, gene duplication mutation and genetic drift. The main objectives of the present study were: a) to perform a sequence analysis of MHC class IIB alleles in European chub (Leuciscus cephalus), b) to investigate the contribution of evolutionary mechanisms (selection, recombination) to MHC diversity, and c) to analyse the co-evolutionary relationship between metazoan parasite load and MHC class IIB alleles. A total of 311 individuals from 15 populations of chub were collected from European rivers across a wide geographical range. (en)
Title
  • Association between major histocompatibility complex class IIB alleles and metazoan parasite load in populations of European chub (Leuciscus cephalus): testing of balancing selection
  • Association between major histocompatibility complex class IIB alleles and metazoan parasite load in populations of European chub (Leuciscus cephalus): testing of balancing selection (en)
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  • Association between major histocompatibility complex class IIB alleles and metazoan parasite load in populations of European chub (Leuciscus cephalus): testing of balancing selection
  • Association between major histocompatibility complex class IIB alleles and metazoan parasite load in populations of European chub (Leuciscus cephalus): testing of balancing selection (en)
skos:notation
  • RIV/00216224:14310/10:00045467!RIV11-GA0-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA524/07/0188), P(LC522), Z(MSM0021622416)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 247953
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  • RIV/00216224:14310/10:00045467
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  • MHC-parasites-freshwater fish (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [3F484435224F]
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
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http://linked.open...iv/tvurceVysledku
  • Jarkovský, Jiří
  • Vetešníková Šimková, Andrea
  • Vyskočilová, Martina
  • Seifertová, Mária
http://linked.open...n/vavai/riv/zamer
http://localhost/t...ganizacniJednotka
  • 14310
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