About: How do cryptosporidia establish their unique niche within the host epithelium?

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cryptosporidia are significant vertebrate pathogens with unique invasion strategy, which, together with phylogenetic analyses suggest a close affinity to gregarines. Electron microscopic observations on 2 evolutionarily distinct gastric species, Cryptosporidium muris from experimentally infected rodents and C. fragile from naturally infected toads, allowed us to map ultrastructural aspects of the cryptosporidian invasion process along with the origin and architecture of parasitophorous sac, and to generalize these observations for gastric cryptosporidia. Both species exhibit a comparable strategy of host cell invasion in which they do not penetrate under the host cell plasma membrane, nor do they come into close contact with the host cytoplasm. Parasite remains attached to the host cell surface, only enveloped by the host membrane folds. Thus, the term epicellular more accurately defines the host compartment within which cryptosporidia reside than does the term intracellular-extracytoplasmic. Cryptosporidia are significant vertebrate pathogens with unique invasion strategy, which, together with phylogenetic analyses suggest a close affinity to gregarines. Electron microscopic observations on 2 evolutionarily distinct gastric species, Cryptosporidium muris from experimentally infected rodents and C. fragile from naturally infected toads, allowed us to map ultrastructural aspects of the cryptosporidian invasion process along with the origin and architecture of parasitophorous sac, and to generalize these observations for gastric cryptosporidia. Both species exhibit a comparable strategy of host cell invasion in which they do not penetrate under the host cell plasma membrane, nor do they come into close contact with the host cytoplasm. Parasite remains attached to the host cell surface, only enveloped by the host membrane folds. Thus, the term epicellular more accurately defines the host compartment within which cryptosporidia reside than does the term intracellular-extracytoplasmic. (en)
Title	How do cryptosporidia establish their unique niche within the host epithelium? How do cryptosporidia establish their unique niche within the host epithelium? (en)
skos:prefLabel	How do cryptosporidia establish their unique niche within the host epithelium? How do cryptosporidia establish their unique niche within the host epithelium? (en)
skos:notation	RIV/00216224:14310/09:00037136!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(LC522), S, Z(MSM0021622416)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Valigurová, Andrea
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	317847
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/09:00037136
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cryptosporidium; epicellular; parasite (en)
http://linked.open.../riv/klicoveSlovo	epicellular Cryptosporidium parasite
http://linked.open...ontrolniKodProRIV	[49CC4C6ACBD2]
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	ICHTHYOPASITOLOGY RESEARCH CENTRE
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Valigurová, Andrea
http://linked.open...n/vavai/riv/zamer	Diversity of Biotic Communities and Populations: Causal Analysis of variation in space and time
http://localhost/t...ganizacniJednotka	14310

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