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rdf:type
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Description
| - Burkholderia cenocepacia is a Gram-negative bacterium that can be found throughout the environment. It is a part of %22Burkholderia cepacia complex%22, which causes potentially deadly problems to patients suffering from cystic fibrosis and chronic granulomatous diseases. A goal of primary importance of this study is the understanding of the molecular mechanisms, especially protein-carbohydrate interactions, which give pathogenic bacterium the ability to invade and colonize its host. Four genes coding protein homologues to the lectin PA-IIL from Pseudomonas aeruginosa have been found in the genome of B. cenocepacia. One of them, BclC, is a 28 kDa protein. The results indicated the unusual binding activity of the protein. The C-terminal domain recognizes D-mannosylated saccharides. Interestingly, the N-terminal domain also displays sugar-binding activity with a strong preference for L-fucosylated oligosaccharides, the Lewis type determinants.
- Burkholderia cenocepacia is a Gram-negative bacterium that can be found throughout the environment. It is a part of %22Burkholderia cepacia complex%22, which causes potentially deadly problems to patients suffering from cystic fibrosis and chronic granulomatous diseases. A goal of primary importance of this study is the understanding of the molecular mechanisms, especially protein-carbohydrate interactions, which give pathogenic bacterium the ability to invade and colonize its host. Four genes coding protein homologues to the lectin PA-IIL from Pseudomonas aeruginosa have been found in the genome of B. cenocepacia. One of them, BclC, is a 28 kDa protein. The results indicated the unusual binding activity of the protein. The C-terminal domain recognizes D-mannosylated saccharides. Interestingly, the N-terminal domain also displays sugar-binding activity with a strong preference for L-fucosylated oligosaccharides, the Lewis type determinants. (en)
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Title
| - Burkholderia cenocepacia and its novel two domain superlectin
- Burkholderia cenocepacia and its novel two domain superlectin (en)
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skos:prefLabel
| - Burkholderia cenocepacia and its novel two domain superlectin
- Burkholderia cenocepacia and its novel two domain superlectin (en)
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skos:notation
| - RIV/00216224:14310/09:00036622!RIV10-MSM-14310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(LC06030), S, Z(MSM0021622413)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/09:00036622
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Burkholderia cenocepacia; lectin; structure function characterisation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Imberty, Anne
- Wimmerová, Michaela
- Šulák, Ondřej
- Delia, Monia
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http://linked.open...vavai/riv/typAkce
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http://linked.open...ain/vavai/riv/wos
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http://linked.open.../riv/zahajeniAkce
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://purl.org/ne...btex#hasPublisher
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http://localhost/t...ganizacniJednotka
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