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  • Dynamic balance between proliferation, differentiation and apoptosis is necessary for healthy intestinal epithelium. Together with endogenous regulators dietary lipid compounds like esential polyunsaturated fatty acids (PUFAs) and short chain fatty acid – butyrate (produced by microbial fermentation of fibre) can play an important role in maintaining homeostasis in this tissue. Signals induced by these factors are integrated inside the cells and may have significant impact on cell metabolism and kinetics. Processes of colon cell differentiation and apoptosis are accompanied with changes of biophysical properties of cell membranes, and by modulation of constitution, structure, symmetry and metabolism of cell lipids.
  • Dynamic balance between proliferation, differentiation and apoptosis is necessary for healthy intestinal epithelium. Together with endogenous regulators dietary lipid compounds like esential polyunsaturated fatty acids (PUFAs) and short chain fatty acid – butyrate (produced by microbial fermentation of fibre) can play an important role in maintaining homeostasis in this tissue. Signals induced by these factors are integrated inside the cells and may have significant impact on cell metabolism and kinetics. Processes of colon cell differentiation and apoptosis are accompanied with changes of biophysical properties of cell membranes, and by modulation of constitution, structure, symmetry and metabolism of cell lipids. (en)
Title
  • Response of normal vs. cancer colon cells to short- and long-chain fatty acids
  • Response of normal vs. cancer colon cells to short- and long-chain fatty acids (en)
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  • Response of normal vs. cancer colon cells to short- and long-chain fatty acids
  • Response of normal vs. cancer colon cells to short- and long-chain fatty acids (en)
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  • RIV/00216224:14310/08:00060308!RIV13-MSM-14310___
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  • RIV/00216224:14310/08:00060308
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  • polyunsaturated fatty acids sodium butyrate colon cancer (en)
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  • [3909FA70EC92]
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  • Hofmanová, Jiřina
  • Kozubík, Alois
  • Skender, Belma
  • Machala, Miroslav
  • Slavík, Josef
  • Cigánek, Miroslav
  • Sovjáková Koubková, Zuzana
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  • 14310
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