About: Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage     Goto   Sponge   NotDistinct   Permalink

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Description
  • Article analyses activation of STAT1 by the six different FGFR3 mutants associated with skeletal dysplasia. We report that only the K650E and K650M mutants activate STAT1. As these mutants represent only a mionority of patients suffering from FGFR3-related skeletal dysplasia, it appears that STAT1 might not be the major intermediate of FGFR3 signaling in cartilage.
  • Article analyses activation of STAT1 by the six different FGFR3 mutants associated with skeletal dysplasia. We report that only the K650E and K650M mutants activate STAT1. As these mutants represent only a mionority of patients suffering from FGFR3-related skeletal dysplasia, it appears that STAT1 might not be the major intermediate of FGFR3 signaling in cartilage. (en)
Title
  • Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage
  • Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage (en)
skos:prefLabel
  • Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage
  • Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage (en)
skos:notation
  • RIV/00216224:14310/08:00024443!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM0021622430)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 355896
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/08:00024443
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • FGFR3; STAT1; activation; skeletal dysplasia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [96B410522F5B]
http://linked.open...i/riv/nazevZdroje
  • PLoS ONE.
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 3
http://linked.open...iv/tvurceVysledku
  • Bryja, Vítězslav
  • Kozubík, Alois
  • Krejčí, Pavel
  • Salašová, Alena
  • Wilcox, William R.
  • Chlebová, Katarína
  • Salazar, Lisa
  • Thompson, Leslie Michels
  • Kashiwada, Tamara A.
http://linked.open...ain/vavai/riv/wos
  • 000265458500007
http://linked.open...n/vavai/riv/zamer
issn
  • 1932-6203
number of pages
http://localhost/t...ganizacniJednotka
  • 14310
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