About: Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2

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About: Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Properly substituted pyrazolo[1,5-a]pyrimidines are potent and selective CDK2 inhibitors. Compound 15j is orally available and showed efficacy in a mouse A2780 xenograft model. Properly substituted pyrazolo[1,5-a]pyrimidines are potent and selective CDK2 inhibitors. Compound 15j is orally available and showed efficacy in a mouse A2780 xenograft model. (en)
Title	Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2 Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2 (en)
skos:prefLabel	Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2 Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2 (en)
skos:notation	RIV/00216224:14310/07:00035878!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	N
http://linked.open...avai/riv/aktivity	N
http://linked.open...iv/cisloPeriodika	17
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Paruch, Kamil
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	446063
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00035878
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CDK2 kinase; inibitor; cancer (en)
http://linked.open.../riv/klicoveSlovo	cancer CDK2 kinase inibitor
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[3BE73928A1DD]
http://linked.open...i/riv/nazevZdroje	Bioorganic & Medicinal Chemistry Letters
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	32 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	2007
http://linked.open...iv/tvurceVysledku	Alvarez, Carmen Dwyer, Michael Fischmann, Thierry Guzi, Timothy Keertikar, Kerry Madison, Vincent Parry, David Paruch, Kamil Rossman, Randall Seghezzi, Wolfgang Wiswell, Derek Brown, Courtney Chan, Tin-Yau Doll, Ronald Hruza, Alan James, Ray Knutson, Chad Lees, Emma McKittrick, Brian Nomeir, Amin Paradkar, Vidyadhar Park, Haengsoon Rivera, Jocelyn Rokosz, Laura Schultz, Lesley Sgambellone, Nicole Stauffer, Tara Tucker, Greg Wang, Yaolin Xu, Xiaoying Zhou, Quiao Shanahan, Fran
http://linked.open...ain/vavai/riv/wos	000250906200036
issn	0960-894X
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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